Mitochondria and microbiota dysfunction in COVID-19 pathogenesis
The COVID-19 pandemic caused by the coronavirus (SARS-CoV-2) has taken the world by
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …
[HTML][HTML] Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder
N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …
impairments in social communication, repetitive behaviors, restricted interests, and …
[HTML][HTML] The role of mitochondria in inflammation: from cancer to neurodegenerative disorders
The main features that are commonly attributed to mitochondria consist of the regulation of
cell proliferation, ATP generation, cell death and metabolism. However, recent scientific …
cell proliferation, ATP generation, cell death and metabolism. However, recent scientific …
[HTML][HTML] Mitochondria in cancer
D Grasso, LX Zampieri, T Capelôa, JA Van de Velde… - Cell stress, 2020 - ncbi.nlm.nih.gov
The rediscovery and reinterpretation of the Warburg effect in the year 2000 occulted for
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …
The peroxisome: an up-and-coming organelle in immunometabolism
Peroxisomes are essential metabolic organelles, well known for their roles in the
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …
[HTML][HTML] Mitochondria and T2D: role of autophagy, ER stress, and inflammasome
M Rocha, N Apostolova, R Diaz-Rua, J Muntane… - Trends in Endocrinology …, 2020 - cell.com
Type 2 diabetes (T2D) is one of the main current threats to human health. Both T2D and its
numerous clinical complications are related to mitochondrial dysfunction and oxidative …
numerous clinical complications are related to mitochondrial dysfunction and oxidative …
[HTML][HTML] Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID-19-associated cardiovascular complications?
AM Darwesh, W Bassiouni, DK Sosnowski… - Pharmacology & …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has currently led to a global pandemic with …
Syndrome Coronavirus 2 (SARS-CoV-2), has currently led to a global pandemic with …
[HTML][HTML] Peroxisomes in immune response and inflammation
The immune response is essential to protect organisms from infection and an altered self. An
organism's overall metabolic status is now recognized as an important and long-overlooked …
organism's overall metabolic status is now recognized as an important and long-overlooked …
[HTML][HTML] STING, the endoplasmic reticulum, and mitochondria: is three a crowd or a conversation?
JA Smith - Frontiers in immunology, 2021 - frontiersin.org
The anti-viral pattern recognition receptor STING and its partnering cytosolic DNA sensor
cGAS have been increasingly recognized to respond to self DNA in multiple pathologic …
cGAS have been increasingly recognized to respond to self DNA in multiple pathologic …
Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells
Vaginal candidiasis is an extremely common disease predominantly caused by four
phylogenetically diverse species: Candida albicans; Candida glabrata; Candida …
phylogenetically diverse species: Candida albicans; Candida glabrata; Candida …