iPSCs-based generation of vascular cells: reprogramming approaches and applications

D Klein - Cellular and Molecular Life Sciences, 2018 - Springer
Recent advances in the field of induced pluripotent stem cells (iPSCs) research have
opened a new avenue for stem cell-based generation of vascular cells. Based on their …

Endothelial progenitor cells: new targets for therapeutics for inflammatory conditions with high cardiovascular risk

N Edwards, AWW Langford-Smith, FL Wilkinson… - Frontiers in …, 2018 - frontiersin.org
Over the past decade, we have witnessed an exponential growth of interest into the role of
endothelial progenitor cells (EPCs) in cardiovascular disease. While the major thinking …

Differences of angiogenesis factors in tumor and diabetes mellitus

S Tan, G Zang, Y Wang, Z Sun, Y Li, C Lu… - … Syndrome and Obesity, 2021 - Taylor & Francis
Angiogenesis, as a process occurring under the regulation of a variety of factors, is one of
the important ways of vascular development. It coexists in a variety of pathological and …

Protective effect and mechanism of lycopene on endothelial progenitor cells (EPCs) from type 2 diabetes mellitus rats

YC Zeng, LS Peng, L Zou, SF Huang, Y Xie… - Biomedicine & …, 2017 - Elsevier
Endothelial progenitor cells (EPCs), widely existing in bone marrow and peripheral blood,
are involved in the repair of injured vascular endothelium and angiogenesis which are …

Exendin-4 reverses high glucose-induced endothelial progenitor cell dysfunction via SDF-1β/CXCR7–AMPK/p38-MAPK/IL-6 axis

Y Yang, Y Zhou, Y Wang, X Wei, L Wu, T Wang, A Ma - Acta diabetologica, 2020 - Springer
Abstract Aim Exendin-4, a glucagon-like peptide-1 (GLP-1) analog, has been used for
treating diabetes mellitus (DM). However, its effects on improving the dysfunction of high …

The role of endothelial progenitor cells in atherosclerosis and impact of anti-lipemic treatments on endothelial repair

V Altabas, LSK Biloš - International journal of molecular sciences, 2022 - mdpi.com
Cardiovascular complications are associated with advanced atherosclerosis. Although
atherosclerosis is still regarded as an incurable disease, at least in its more advanced …

[HTML][HTML] Neuregulin-1 promotes myocardial angiogenesis in the rat model of diabetic cardiomyopathy

C Gui, Z Zeng, Q Chen, Y Luo, L Li… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Microvascular insufficiency takes a critical role in the development of
diabetic cardiomyopathy (DCM). So this study was designed to investigate the effects of …

Cardiac biomarkers in diabetes mellitus: new dawn for risk stratification?

AE Berezin - Diabetes & Metabolic Syndrome: Clinical Research & …, 2017 - Elsevier
Type 2 diabetes mellitus (T2DM) remains a leading cause of cardiovascular (CV) events and
diseases worldwide. The aim of the review is to summarize our knowledge regarding clinical …

Altered signature of apoptotic endothelial cell-derived microvesicles predicts chronic heart failure phenotypes

AE Berezin, AA Kremzer, TA Samura… - Biomarkers in …, 2019 - Taylor & Francis
Aim: to evaluate the associations between signatures of apoptotic endothelial cell-derived
microvesicles (MVs) with phenotypes of chronic heart failure (HF). Methods: The study …

MiR-27b augments bone marrow progenitor cell survival via suppressing the mitochondrial apoptotic pathway in Type 2 diabetes

H Li, J Liu, Y Wang, Z Fu… - American Journal …, 2017 - journals.physiology.org
Bone marrow-derived progenitor cells (BMPCs) are potential candidates for autologous cell
therapy in tissue repair and regeneration because of their high angiogenic potential …