Knee osteoarthritis (KOA) is a chronic joint bone disease characterized by inflammatory
destruction and hyperplasia of bone. Its main clinical symptoms are joint mobility difficulties …

The state of host cells is reflected in the cargo carried by their extracellular vesicles (EVs).
This makes EV a potential source of biomarkers for human diseases. Piwi-interacting RNA …

Long noncoding RNAs (lncRNAs) have emerged as important regulators of osteoarthritis
(OA), but the biological roles and clinical significance of most lncRNAs in OA are not fully …

Aim: To investigate whether kaempferol exhibited protective effects on osteoarthritis
chondrocytes by modulating the XIST/miR-130a/STAT3 axis. Methods: qRT-PCR and …

Autophagy, as a fundamental mechanism for cellular homeostasis, is generally involved in
the occurrence and progression of various diseases. Osteoarthritis (OA) is the most common …

Osteoarthritis is a progressive and heterogeneous joint disease with complex pathogenesis.
The various phenotypes associated with each patient suggest that better subgrouping of …

Summary HS3ST3B1-IT1 was identified as a downregulated long noncoding RNA in
osteoarthritic cartilage. However, its roles and mechanisms in the pathogenesis of …

Aims Circular RNA (circRNA) is involved in the regulation of articular cartilage degeneration
induced by inflammatory factors or oxidative stress. In a previous study, we found that the …

Background Osteoarthritis (OA) is characterized by chondrocyte injury. Circular RNAs
(circRNAs) are involved in the pathogenesis of various diseases, including OA. The purpose …

Objective This study explores LncRNA TM1‐3P effects on the proliferation, apoptosis, and
inflammatory response of fibroblasts in osteoarthritis (OA) and its underlying mechanism …