lncRNA-microRNA axis in cancer drug resistance: particular focus on signaling pathways

RO Saleh, MTS Al-Ouqaili, E Ali, S Alhajlah… - Medical Oncology, 2024 - Springer
Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …

Non-coding RNAs: a new frontier in benzene-mediated toxicity

AHS Nia, M Reyhani-Ardabili, M Sheikhvand… - Toxicology, 2023 - Elsevier
One of the most frequent environmental contaminants, benzene is still widely used as an
industrial solvent around the world, especially in developing nations, posing a serious …

[HTML][HTML] Crosstalk between MiRNAs/lncRNAs and PI3K/AKT signaling pathway in diabetes mellitus: Mechanistic and therapeutic perspectives

SM Aghaei-Zarch - Non-Coding RNA Research, 2024 - Elsevier
Diabetes as a fastest growing diseases worldwide is characterized by elevated blood
glucose levels. There's an enormous financial burden associated with this endocrine …

The correlation between echinoderms diversity and physicochemical parameters in marine pollution: A case study of the Persian Gulf coastline

S Soltani, ER Ghatrami, SMB Nabavi, N Khorasani… - Marine Pollution …, 2024 - Elsevier
This study was conducted with the aim of investigating the correlation between echinoderms
diversity and physicochemical parameters in the Persian Gulf coastline in Bushehr province …

Exosomal miR-122-3p represses the growth and metastasis of MCF-7/ADR cells by targeting GRK4-mediated activation of the Wnt/β-catenin pathway

B Song, G Hou, M Xu, M Chen - Cellular Signalling, 2024 - Elsevier
Breast cancer (BC) is a common cancer whose incidence continues to grow while its
medical progress has stagnated. miRNAs are vital messengers that facilitate …

A pro-death autophagy-based nanoplatform for enhancing antitumour efficacy with improved immune responses

Y Li, X Du, X Kong, Y Fang, Z He, D Liu, H Wu… - European Journal of …, 2024 - Elsevier
Due to the pro-survival effect of mild autophagy, the therapeutic effect of chemo-
immunotherapy is unsatisfactory. In addition, the adverse tumour microenvironment (TME) …

Therapeutic effects of garlic (Allium sativum) on female reproductive system: A systematic review

F Jafari, S Khalilzadeh, F Nejatbakhsh - Heliyon, 2023 - cell.com
Complementary and alternative medicine, including Persian medicine (PM), offers a variety
of disease prevention and treatment methods, including the application of medicinal plants …

Circulating vitamin D level before initiating chemotherapy impacts on the time-to-outcome in metastatic colorectal cancer patients: systematic review and meta …

A Ottaiano, ML Iacovino, M Santorsola… - Journal of Translational …, 2024 - Springer
Abstract Background Vitamin D (VD) is implicated in various health conditions, including
colorectal cancer (CRC). To investigate potential relationships between pre-chemotherapy …

LRRC8A as a central mediator promotes colon cancer metastasis by regulating PIP5K1B/PIP2 pathway

H Zhang, R Liu, Z Jing, C Li, W Fan, H Li, H Li… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Colorectal cancer (CRC) has been the third most common malignancy and the second
cause of cancer-related mortality. As the core of volume-sensitive chloride currents, leucine …

CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis

SK Yu, T Yu, YM Wang, A Sun, J Liu, KH Lu - Journal of Translational …, 2024 - Springer
Abstract Background Chaperonin Containing TCP1 Subunit 6 A (CCT6A) is a prominent
protein involved in the folding and stabilization of newly synthesized proteins. However, its …