Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain
disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's …

In the past century, noncommunicable diseases have surpassed infectious diseases as the
principal cause of sickness and death, worldwide. Trillions of commensal microbes live in …

Schizophrenia is a major mental illness characterized by positive and negative symptoms,
and by cognitive deficit. Although cognitive impairment is disabling for patients, it has been …

Alzheimer's disease (AD) is a neurodegenerative disorder characterised by impairments in
the cognitive domains associated with orientation, recording, and memory. This pathology …

Schizophrenia, a neuropsychiatric disorder has been associated with aberrant
neurotransmission affecting behaviors, social preference, and cognition. Limitations in …

Ethnopharmacological relevance Persistent ketamine insults to the central nervous system
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …

Ketamine is a dissociative anaesthetic agent whose recreational use amongst adolescents
and young adults is reaching epidemic proportions in a number of countries. While animal …

Schizophrenia (SCZ) is a severe neurodevelopmental disorder affecting 1% of populations
worldwide with a grave disability and socioeconomic burden. Current antipsychotic …

Despite the existence of many preclinical studies, scientific evidence is lacking on the
clinical use of alpha-lipoic acid (ALA) for central nervous system disorders. Therefore, we …

Evidence derived from preliminary studies suggests that morin, a neuroactive flavonoid with
proven antioxidant and antiinflammatory properties possess antipsychotic-like activity. The …