[HTML][HTML] Intranasal COVID-19 vaccines: From bench to bed
A Alu, L Chen, H Lei, Y Wei, X Tian, X Wei - EBioMedicine, 2022 - thelancet.com
Currently licensed COVID-19 vaccines are all designed for intramuscular (IM) immunization.
However, vaccination today failed to prevent the virus infection through the upper respiratory …
However, vaccination today failed to prevent the virus infection through the upper respiratory …
[HTML][HTML] Mucosal vaccines, sterilizing immunity, and the future of SARS-CoV-2 virulence
Sterilizing immunity after vaccination is desirable to prevent the spread of infection from
vaccinees, which can be especially dangerous in hospital settings while managing frail …
vaccinees, which can be especially dangerous in hospital settings while managing frail …
[HTML][HTML] Mucosal immune response in BNT162b2 COVID-19 vaccine recipients
L Azzi, D Dalla Gasperina, G Veronesi, M Shallak… - …, 2022 - thelancet.com
Background Although the BNT162b2 COVID-19 vaccine is known to induce IgG neutralizing
antibodies in serum protecting against COVID-19, it has not been studied in detail whether it …
antibodies in serum protecting against COVID-19, it has not been studied in detail whether it …
[HTML][HTML] Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections
S Terreri, EP Mortari, MR Vinci, C Russo, C Alteri… - Cell host & …, 2022 - cell.com
Breakthrough SARS-CoV-2 infections in fully vaccinated individuals are considered a
consequence of waning immunity. Serum antibodies represent the most measurable …
consequence of waning immunity. Serum antibodies represent the most measurable …
COVID-19 intranasal vaccines: current progress, advantages, prospects, and challenges
Multiple vaccines have recently been developed, and almost all the countries are presently
vaccinating their population to tackle the COVID-19 pandemic. Most of the COVID-19 …
vaccinating their population to tackle the COVID-19 pandemic. Most of the COVID-19 …
[HTML][HTML] SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential therapies
AM Almehdi, G Khoder, AS Alchakee, AT Alsayyid… - Infection, 2021 - Springer
Purpose COVID-19 pandemic has emerged as a result of infection by the deadly pathogenic
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats …
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats …
[HTML][HTML] Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines
V Mouro, A Fischer - Mucosal immunology, 2022 - Elsevier
The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
[HTML][HTML] Highly specific memory B cells generation after the 2nd dose of BNT162b2 vaccine compensate for the decline of serum antibodies and absence of mucosal …
E Piano Mortari, C Russo, MR Vinci, S Terreri… - Cells, 2021 - mdpi.com
Specific memory B cells and antibodies are a reliable read-out of vaccine efficacy. We
analysed these biomarkers after one and two doses of BNT162b2 vaccine. The second dose …
analysed these biomarkers after one and two doses of BNT162b2 vaccine. The second dose …
COVID-19 and vaccination: myths vs science
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …
Oral and intranasal vaccines against SARS‐CoV‐2: Current progress, prospects, advantages, and challenges
Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
caused a deadly pandemic in the 21st century, resulting in many deaths, economic loss, and …
caused a deadly pandemic in the 21st century, resulting in many deaths, economic loss, and …