Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system
N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …
mammals. It is produced by mammalian cells and tissues by various enzymes …
International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
[HTML][HTML] Cysteine metabolic circuitries: Druggable targets in cancer
VDB Bonifácio, SA Pereira, J Serpa… - British journal of cancer, 2021 - nature.com
To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
Regulators of the transsulfuration pathway
The transsulfuration pathway is a metabolic pathway where transfer of sulfur from
homocysteine to cysteine occurs. The pathway leads to the generation of several sulfur …
homocysteine to cysteine occurs. The pathway leads to the generation of several sulfur …
[HTML][HTML] Hydrogen sulfide biology and its role in cancer
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …
[HTML][HTML] Hydrogen sulfide signaling in mitochondria and disease
B Murphy, R Bhattacharya, P Mukherjee - The FASEB Journal, 2019 - ncbi.nlm.nih.gov
Hydrogen sulfide can signal through 3 distinct mechanisms: 1) reduction and/or direct
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …
A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator
C Szabo - Biochemical pharmacology, 2018 - Elsevier
The history of H 2 S–as an environmental toxin–dates back to 1700, to the observations of
the Italian physician Bernardino Ramazzini, whose book “De Morbis Artificum Diatriba” …
the Italian physician Bernardino Ramazzini, whose book “De Morbis Artificum Diatriba” …
[HTML][HTML] Hydrogen sulfide and vascular regulation–An update
B Lv, S Chen, C Tang, H Jin, J Du, Y Huang - Journal of advanced research, 2021 - Elsevier
Abstract Background Hydrogen sulfide (H 2 S) is considered to be the third gasotransmitter
after carbon monoxide (CO) and nitric oxide (NO). It plays an important role in the regulation …
after carbon monoxide (CO) and nitric oxide (NO). It plays an important role in the regulation …
[HTML][HTML] Hydrogen sulfide biochemistry and interplay with other gaseous mediators in mammalian physiology
A Giuffrè, JB Vicente - Oxidative Medicine and Cellular Longevity, 2018 - hindawi.com
Hydrogen sulfide (H 2 S) has emerged as a relevant signaling molecule in physiology,
taking its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide …
taking its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide …