Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?
V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
Immunosenescence: A systems-level overview of immune cell biology and strategies for improving vaccine responses
SN Crooke, IG Ovsyannikova, GA Poland… - Experimental …, 2019 - Elsevier
Immunosenescence contributes to a decreased capacity of the immune system to respond
effectively to infections or vaccines in the elderly. The full extent of the biological changes …
effectively to infections or vaccines in the elderly. The full extent of the biological changes …
The role of innate immunity in natural elite controllers of HIV-1 infection
Y Shi, J Su, R Chen, W Wei, Z Yuan, X Chen… - Frontiers in …, 2022 - frontiersin.org
The natural process of human immunodeficiency virus type 1 (HIV-1) infection is
characterized by high viral load, immune cell exhaustion, and immunodeficiency, which …
characterized by high viral load, immune cell exhaustion, and immunodeficiency, which …
HIV-associated cellular senescence: a contributor to accelerated aging
J Cohen, C Torres - Ageing research reviews, 2017 - Elsevier
Due to the advent of antiretroviral therapy HIV is no longer a terminal disease and the HIV
infected patients are becoming increasingly older. While this is a major success, with …
infected patients are becoming increasingly older. While this is a major success, with …
Extrapolating understanding of food risk perceptions to emerging food safety cases
Important determinants of risk perceptions associated with foods are the extent to which the
potential hazards are perceived to have technological or naturally occurring origins, together …
potential hazards are perceived to have technological or naturally occurring origins, together …
Patho-physiology of aging and immune-senescence: possible correlates with comorbidity and mortality in middle-aged and old COVID-19 patients
During the last 2 years, the entire world has been severely devastated by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic (COVID-19) as it resulted in …
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic (COVID-19) as it resulted in …
Evidence for residual immunity to smallpox after vaccination and implications for re-emergence
Introduction Smallpox has been eradicated but advances in synthetic biology have
increased the risk of its re-emergence. Residual immunity in individuals who were …
increased the risk of its re-emergence. Residual immunity in individuals who were …
[HTML][HTML] Aged mice are more resistant to influenza virus infection due to reduced inflammation and lung pathology
J Lu, X Duan, W Zhao, J Wang, H Wang, K Zhou… - Aging and …, 2018 - ncbi.nlm.nih.gov
Immune responses are a double-edged sword. Effective and appropriate immune responses
capable of controlling viral infection while also largely preserving tissue integrity, are critical …
capable of controlling viral infection while also largely preserving tissue integrity, are critical …
Impact of Trypanosoma cruzi infection on nitric oxide synthase and arginase expression and activity in young and elderly mice
AA Felizardo, IS Caldas, AAS Mendonça… - Free Radical Biology …, 2018 - Elsevier
Elderly organisms are more susceptible to infectious diseases. However, the impact of aging
on antiparasitic mechanisms, especially the nitric oxide pathway, is poorly understood …
on antiparasitic mechanisms, especially the nitric oxide pathway, is poorly understood …
Biobran/MGN-3, an arabinoxylan rice bran, enhances NK cell activity in geriatric subjects: A randomized, double‑blind, placebo-controlled clinical trial
Aging is associated with a decline in natural killer (NK) and natural killer T (NKT) cell
function that may contribute to increased susceptibility to malignancy and infection. A …
function that may contribute to increased susceptibility to malignancy and infection. A …