[HTML][HTML] Discogenic back pain: update on treatment
E Remotti, C Nduaguba, PA Woolley… - Orthopedic …, 2023 - ncbi.nlm.nih.gov
Despite the scarcity of data for the treatment of DBP, treatments do exist with varying efficacy
for DBP. Novel techniques such as the use of biologics may provide another avenue for …
for DBP. Novel techniques such as the use of biologics may provide another avenue for …
Injectable Inflammation‐Responsive Hydrogels for Microenvironmental Regulation of Intervertebral Disc Degeneration
L Liu, W Wang, L Huang, Y Xian, W Ma… - Advanced …, 2024 - Wiley Online Library
Chronic local inflammation and excessive cell apoptosis in nucleus pulposus (NP) tissue are
the main causes of intervertebral disc degeneration (IDD). Stimuli‐responsive hydrogels …
the main causes of intervertebral disc degeneration (IDD). Stimuli‐responsive hydrogels …
Does vertebral osteoporosis delay or accelerate lumbar disc degeneration? A systematic review
W Li, H Zhao, S Zhou, Z Xiong, W Zhong, J Guan… - Osteoporosis …, 2023 - Springer
The effect of vertebral osteoporosis on disc degeneration is still debated. The purpose of this
study was to provide a systematic review of studies in this area to further reveal the …
study was to provide a systematic review of studies in this area to further reveal the …
Mitochondrial dysfunction: a new molecular mechanism of intervertebral disc degeneration
C Song, Y Xu, Q Peng, R Chen, D Zhou, K Cheng… - Inflammation …, 2023 - Springer
Objective Intervertebral disc degeneration (IVDD) is a chronic degenerative orthopedic
illness that causes lower back pain as a typical clinical symptom, severely reducing patients' …
illness that causes lower back pain as a typical clinical symptom, severely reducing patients' …
Role of arachidonic acid metabolism in intervertebral disc degeneration: identification of potential biomarkers and therapeutic targets via multi-omics analysis and …
J Tan, M Shi, B Li, Y Liu, S Luo, X Cheng - Lipids in Health and Disease, 2023 - Springer
Background Intervertebral disc degeneration (IVDD) is widely recognized as the primary
etiological factor underlying low back pain, often necessitating surgical intervention as the …
etiological factor underlying low back pain, often necessitating surgical intervention as the …
Application of mesenchymal stem cell-derived exosomes from different sources in intervertebral disc degeneration
Y Xia, R Yang, Y Hou, H Wang, Y Li, J Zhu… - … in bioengineering and …, 2022 - frontiersin.org
Intervertebral disc degeneration (IVDD) is a main cause of lower back pain, leading to
psychological and economic burdens to patients. Physical therapy only delays pain in …
psychological and economic burdens to patients. Physical therapy only delays pain in …
Nucleus pulposus cell-derived efficient microcarrier for intervertebral disc tissue engineering
X Zhou, N Shen, Y Tao, J Wang, K Xia, L Ying… - …, 2023 - iopscience.iop.org
Adipose-derived stem cells (ADSCs) show great potential for the treatment of intervertebral
disc (IVD) degeneration. An ideal carrier is necessary to transplant ADSCs into degenerated …
disc (IVD) degeneration. An ideal carrier is necessary to transplant ADSCs into degenerated …
MicroRNA-targeting nanomedicines for the treatment of intervertebral disc degeneration
Low back pain stands as a pervasive global health concern, afflicting almost 80% of adults
at some point in their lives with nearly 40% attributable to intervertebral disc degeneration …
at some point in their lives with nearly 40% attributable to intervertebral disc degeneration …
Increased expression of inflammatory cytokines and discogenic neck pain
X Kang, M Qian, T Qin, M Liu, H Xu… - Orthopaedic Surgery, 2024 - Wiley Online Library
Objective Although neck pain has become a serious economic and social problem
worldwide, the etiology remains poorly understood. The aim of current study is to explore the …
worldwide, the etiology remains poorly understood. The aim of current study is to explore the …
USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic …
X Li, J Zhang, B Wang, C Chen, E Zhang, Z Lv, Q He… - Biology Direct, 2023 - Springer
Background Intervertebral disc degeneration (IDD) naturally occurs during the aging
process. Its occurrence is closely related to chronic inflammation; however, the causal …
process. Its occurrence is closely related to chronic inflammation; however, the causal …