Oxidative stress is one of the main driving mechanisms of intervertebral disc degeneration
(IDD). Oxidative stress has been associated with inflammation in the intervertebral disc …

The treatment of intervertebral disc degeneration (IVDD) using bone marrow mesenchymal
stem cell‐derived exosomes has shown success in alleviating inflammation and restoring …

Intervertebral disc degeneration (IVDD) is commonly associated with many spinal problems,
such as low back pain, and significantly impacts a patient's quality of life. However, current …

Background. With the extensive development of intervertebral disc degeneration (IDD)
research, IDD has been found to be a complex disease associated with immune‐related …

Degradation of extracellular matrix (ECM), reactive oxygen species (ROS) production, and
inflammation are critical players in the pathogenesis of intervertebral disc degeneration …

Methods Single-cell transcriptomics and high-throughput transcriptomics were used to
screen factors significantly correlated with intervertebral disc degeneration (IDD) …

Nucleus pulposus (NP) discectomy is a clinical procedure for the treatment of late-stage
intervertebral disc (IVD) degeneration; however, it is associated with the potential for serious …

Intervertebral disc degeneration (IVDD) is the pathological basis of a range of degenerative
spinal diseases and is the primary cause of lower back pain. Mesenchymal stem cell (MSC) …

There have been an increasing number of patients with degenerative disc diseases due to
the aging population. In light of this, studies on the pathogenesis of intervertebral disc …

Objective Multiple‐level Intervertebral disc degeneration (IDD) in patients with lumbar disc
herniation (LDH) is related to postoperative re‐herniation and low back pain. Although many …