[HTML][HTML] How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration
QX Zhang, M Cui - World Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
Intervertebral disc (ID) degeneration (IDD) is one of the main causes of chronic low back
pain, and degenerative lesions are usually caused by an imbalance between catabolic and …
pain, and degenerative lesions are usually caused by an imbalance between catabolic and …
The role of sirtuins in intervertebral disc degeneration: Mechanisms and therapeutic potential
H Tu, Q Gao, Y Zhou, L Peng, D Wu… - Journal of Cellular …, 2024 - Wiley Online Library
Intervertebral disc degeneration (IDD) is one of the main causes of low back pain, which
affects the patients' quality of life and health and imposes a significant socioeconomic …
affects the patients' quality of life and health and imposes a significant socioeconomic …
Stimuli-Responsive Delivery Systems for Intervertebral Disc Degeneration
J Tang, Y Luo, Q Wang, J Wu, Y Wei - International Journal of …, 2024 - Taylor & Francis
As a major cause of low back pain, intervertebral disc degeneration is an increasingly
prevalent chronic disease worldwide that leads to huge annual financial losses. The …
prevalent chronic disease worldwide that leads to huge annual financial losses. The …
Evolving role of viadisc for chronic low back and discogenic pain: a narrative review
JK Tolson, RL Menuet, GH Ly, BA Chanes… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Chronic lower back pain is a leading cause of disability and healthcare
spending worldwide. Discogenic pain, pain originating from the intervertebral disk, is a …
spending worldwide. Discogenic pain, pain originating from the intervertebral disk, is a …
ALKBH5-mediated m6A demethylation of Runx2 mRNA promotes extracellular matrix degradation and intervertebral disc degeneration
Y Lei, E Zhan, C Chen, Y Hu, Z Lv, Q He, X Wang, X Li… - Cell & Bioscience, 2024 - Springer
Abstract Background N6-methyladenosine (m6A) methylation is a prevalent RNA
modification implicated in various diseases. However, its role in intervertebral disc …
modification implicated in various diseases. However, its role in intervertebral disc …
The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future …
Y Hu, R Yang, S Liu, Z Song… - Drug Design, Development …, 2024 - Taylor & Francis
Low back pain (LBP) is a common condition that has substantial consequences on
individuals and society, both socially and economically. The primary contributor to LBP is …
individuals and society, both socially and economically. The primary contributor to LBP is …
Roles of ferroptosis in intervertebral disc degeneration and osteoarthritis
Z Xiong, H Sun, M Liu, Y Zhuang - Chinese Journal of Tissue Engineering …, 2023 - cjter.com
BACKGROUND: Ferroptosis is a new type of programmed cell death, distinguished from
apoptosis, autophagy and pyroptosis, which is characterized by the iron-dependent …
apoptosis, autophagy and pyroptosis, which is characterized by the iron-dependent …
The MnO2/GelMA Composite Hydrogels Improve the ROS Microenvironment of Annulus Fibrosus Cells by Promoting the Antioxidant and Autophagy through the …
B Xu, M Huang, J Li, Q Meng, J Hu, Q Chen, H He… - Gels, 2024 - mdpi.com
Intervertebral disc degeneration (IVDD) is a worldwide disease that causes low back pain
and reduces quality of life. Biotherapeutic strategies based on tissue engineering …
and reduces quality of life. Biotherapeutic strategies based on tissue engineering …
Potential use of extracellular vesicles in the treatment of intervertebral disc degeneration
Q Li, R Guo, Z Wu, C Shen - Tissue Engineering Part C: Methods, 2024 - liebertpub.com
Intervertebral disc degeneration (IVDD) is a major cause of low back pain, and several
studies have evaluated the efficacy of extracellular vesicles (EVs) in the treatment of IVDD …
studies have evaluated the efficacy of extracellular vesicles (EVs) in the treatment of IVDD …
Bioinformatics‐based discovery of intervertebral disc degeneration biomarkers and immune‐inflammatory infiltrates
C Song, D Zhou, K Cheng, F Liu, W Cai, Y Mei… - JOR …, 2024 - Wiley Online Library
Background Intervertebral disc degeneration (IVDD) is a common chronic disease in
orthopedics, and its molecular mechanisms are still not well explained. Aim This study's …
orthopedics, and its molecular mechanisms are still not well explained. Aim This study's …