Acetaminophen/paracetamol is the most widely used drug of the world. At the same time, it is
probably one of the most dangerous compounds in medical use, causing hundreds of …

The goal of this document is to update the original OARSI recommendations specifically for
the design, conduct, and reporting of clinical trials that target symptom or structure …

Background: The Massachusetts 2006 health care reform has been called a model for the
Affordable Care Act. The law attained near-universal insurance coverage and increased …

Objective A meta analysis to compare efficacy and safety of intraarticular hyaluronic acid
(HA) and intraarticular corticosteroids (CS) in patients with knee osteoarthritis. Method …

Viscosupplementation (VS) with hyaluronic acid is currently used by physicians to treat
osteoarthritis. However, many aspects of this treatment remain questionable and subject of …

Background: Knee osteoarthritis (OA) is a common and often disabling joint disorder among
adults that may result in impaired activity and daily function. A variety of treatment options …

Objectives Systematically review the qualitative literature on living with knee osteoarthritis
from patient and carer perspectives. Design Systematic review of qualitative studies. Five …

Background: Few remedies effectively treat long-term pain and disability from knee
osteoarthritis. Studies suggest that Tai Chi alleviates symptoms, but no trials have directly …

Osteoarthritis (OA) is an aging-related joint disease, pathologically featured with
degenerated articular cartilage and deformation of subchondral bone. OA has become the …

Osteoarthritis results in irreparable loss of articular cartilage. Due to its avascular nature and
low mitotic activity, cartilage has little intrinsic capacity for repair. Cartilage loss leads to pain …