Molecular, functional, and histopathological classification of the pituitary neuroendocrine neoplasms

C Inomoto, S Tahara, K Oyama, M Kimura… - Brain Tumor …, 2021 - Springer
In 2017, WHO published an updated classification of the pituitary adenomas according to
the lineages defined by the transcription factors, PIT1, SF1 and TPIT. Nomenclature of the …

Towards precision medicine for clinically non‐functioning pituitary tumours

NF Lenders, WJ Inder, AI McCormack - Clinical Endocrinology, 2021 - Wiley Online Library
Objective Clinically non‐functioning pituitary tumours (NFPT) are a heterogenous group of
neoplasms with diverse outcomes. The purpose of this narrative review was to summarize …

[HTML][HTML] Co-occurrence of functional gonadotroph adenoma and lactotroph adenoma: A case report and literature review

MT Ullah, MBS Lopes, JA Jane Jr, GK Hong… - AACE Clinical Case …, 2023 - Elsevier
Abstract Background/Objective Functional gonadotroph adenomas (FGAs) are adenomas
producing active gonadotropins, follicle-stimulating hormone or luteinizing hormone. Double …

Elevated risk of recurrence and retreatment for silent pituitary adenomas

S Gupta, SE Hoffman, NH Mehta, B Hauser, M Altshuler… - Pituitary, 2024 - Springer
Purpose Pituitary adenomas are the most common tumor of the pituitary gland and comprise
nearly 15% of all intracranial masses. These tumors are stratified into functional or silent …

Up-regulation of 15-lipoxygenase enzymes and products in functional and non-functional pituitary adenomas

AB Barooni, M Ghorbani, V Salimi… - Lipids in Health and …, 2019 - Springer
Background Pituitary adenoma accounts as a complex and multifactorial intracranial
neoplasm with wide range of clinical symptoms which its underlying molecular mechanism …

Heterogeneity of TPIT expression in ACTH-secreting extra-pituitary neuroendocrine tumors (NETs) supports the existence of different cellular programs in pancreatic …

S Uccella, E Leoni, S Kaiser, R Maragliano, A Valerio… - Virchows Archiv, 2023 - Springer
Extra-pituitary ACTH secretion is associated with a variety of neoplastic conditions and may
cause the so-called ectopic ACTH-dependent Cushing syndrome (CS). The clarification of …

[HTML][HTML] Quantitative magnetic resonance-derived biomarkers as predictors of function and histotype in adenohypophyseal tumours

D Lewis, F Roncaroli, T Kearney, DJ Coope… - …, 2022 - karger.com
Introduction: Magnetic resonance imaging (MRI) is the main modality to diagnose
adenohypophyseal tumours, while biochemical assessment of pituitary hormones allows for …

[HTML][HTML] Functioning gonadotroph adenoma with hyperestrogenemia and ovarian hyperstimulation in a reproductive-aged woman: a case report and review of …

Y He, YT Gao, L Sun - World Journal of Clinical Cases, 2023 - ncbi.nlm.nih.gov
BACKGROUND Functioning gonadotroph adenomas are extremely rare pituitary tumors that
secrete gonadotropins and exhibit distinct clinical manifestations. Here, we report a case of …

Current opinion on the diagnosis and management of non-functioning pituitary adenomas

EB Lamback, LE Wildemberg… - Expert Review of …, 2021 - Taylor & Francis
Introduction Non-functioning pituitary adenomas (NFPAs) are clinically silent tumors and the
second most common pituitary adenoma. Surgery is the mainstay of treatment as there is, as …

Suspected silent pituitary somatotroph neuroendocrine tumor associated with acromegaly-like bone disorders: a case report

T Xiao, X Mao, O Wang, Y Yao, K Deng, H Zhu… - BMC Endocrine …, 2024 - Springer
Background Growth hormone (GH) positive pituitary neuroendocrine tumors do not always
cause acromegaly. Approximately one-third of GH-positive pituitary tumors are classified as …