Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions …

Impact of parental rheumatoid arthritis on risk of autism spectrum disorders in offspring: A systematic review and meta-analysis

CK Sun, YS Cheng, IW Chen, HJ Chiu, W Chung… - Frontiers in …, 2022 - frontiersin.org
Background To investigate the association of risk of offspring autism spectrum disorder
(ASD) with both maternal and paternal rheumatoid arthritis (RA). Methods The Embase …

Parental inflammatory bowel disease and autism in children

A Sadik, C Dardani, P Pagoni, A Havdahl… - Nature medicine, 2022 - nature.com
Evidence linking parental inflammatory bowel disease (IBD) with autism in children is
inconclusive. We conducted four complementary studies to investigate associations …

Association of maternal autoimmune diseases with risk of mental disorders in offspring in Denmark

H He, Y Yu, Z Liew, M Gissler, KD László… - JAMA network …, 2022 - jamanetwork.com
Importance Maternal immune activation during pregnancy is associated with increased risks
of several mental disorders in offspring during childhood, but little is known about how …

Maternal rheumatoid arthritis and risk of autism in the offspring

W Yin, M Norrbäck, SZ Levine, N Rivera… - Psychological …, 2023 - cambridge.org
BackgroundMaternal Rheumatoid Arthritis (RA) is suggested to increase the risk of Autism
Spectrum Disorder (ASD) in the offspring, mainly through inflammation/autoimmunity, but the …

[HTML][HTML] TH1/Treg ratio may be a marker of autism in children with immune dysfunction

ZQ Nie, D Han, K Zhang, M Li, HK Kwon, SH Im… - Research in Autism …, 2023 - Elsevier
Evidence suggests a link between autism spectrum disorder (ASD), behavioral symptoms in
the context of ASD, and presence of an altered immune function. Several studies have …

Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population‐based cohort study

TC Nielsen, N Nassar, AW Shand, HF Jones… - Autism …, 2022 - Wiley Online Library
The aim of this study was to examine potential synergistic effects between maternal
autoimmune disease and early childhood infections and their association with autism …

Familial co-aggregation of attention-deficit/hyperactivity disorder and autoimmune diseases: a cohort study based on Swedish population-wide registers

TA Hegvik, Q Chen, R Kuja-Halkola… - International Journal …, 2022 - academic.oup.com
Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with
several autoimmune diseases (AD), both within individuals and across relatives, implying …

The mental and physical health profiles of older adults who endorse elevated autistic traits

GR Stewart, A Corbett, C Ballard… - The Journals of …, 2021 - academic.oup.com
Objectives The mental and physical health profile of autistic people has been studied in
adolescence and adulthood, with elevated rates of most conditions being reported …

Multiple risk factors: A challenge in the management of Autism

MS Nadeem, FA Al-Abbasi, I Kazmi… - Current …, 2020 - ingentaconnect.com
Autism Spectrum Disorder (ASD) is an emerging health problem involving 1 out of every 68
children. The incidence rate of autism has increased 3 folds during the last 3 decades. Due …