[HTML][HTML] Endometrial stem cells: Orchestrating dynamic regeneration of Endometrium and their implications in Diverse Endometrial disorders

IS Hong - International Journal of Biological Sciences, 2024 - ncbi.nlm.nih.gov
The human endometrium, a vital component of the uterus, undergoes dynamic changes
during the menstrual cycle to create a receptive environment for embryo implantation. Its …

[HTML][HTML] Features of the immunosuppressive tumor microenvironment in endometrial cancer based on molecular subtype

C Zhang, M Wang, Y Wu - Frontiers in Oncology, 2023 - frontiersin.org
Endometrial cancer (EC) is one of the three most prevalent gynecological tumors affecting
women and is the most prevalent gynecological malignancy in the developed world. Its …

GTAD: a graph-based approach for cell spatial composition inference from integrated scRNA-seq and ST-seq data

T Zhang, Z Zhang, L Li, B Dong, G Wang… - Briefings in …, 2024 - academic.oup.com
With the emergence of spatial transcriptome sequencing (ST-seq), research now heavily
relies on the joint analysis of ST-seq and single-cell RNA sequencing (scRNA-seq) data to …

[HTML][HTML] Exploring distinct properties of endometrial stem cells through advanced single-cell analysis platforms

JW Lee, HY Lee - Stem Cell Research & Therapy, 2023 - Springer
The endometrium is a dynamic tissue that undergoes cyclic changes in response to ovarian
hormones during the menstrual cycle. These changes are crucial for pregnancy …

[HTML][HTML] RNA modification gene WDR4 facilitates tumor progression and immunotherapy resistance in breast cancer

Y Luo, W Tian, D Kang, L Wu, H Tang, S Wang… - Journal of Advanced …, 2024 - Elsevier
Introduction Growing interest toward RNA modification in cancer has inspired the
exploration of datasets related to multiple RNA modifications. However, a comprehensive …

Targeting cellular senescence as a therapeutic vulnerability in gastric cancer

H Geng, C Huang, L Xu, Y Zhou, Z Dong, Y Zhong, Q Li… - Life Sciences, 2024 - Elsevier
Aims Cellular senescence (CS) represents an intracellular defense mechanism responding
to stress signals and can be leveraged as a “vulnerability” in cancer treatment. This study …

[HTML][HTML] Characterization of genomic instability-related genes predicts survival and therapeutic response in lung adenocarcinoma

S Li, W Wang, H Yu, S Zhang, W Bi, S Sun, B Hong… - BMC cancer, 2023 - Springer
Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell
lung cancer (NSCLC) and is the leading cause of cancer death worldwide. Its progression is …

Single-cell RNA-seq reveals MIF−(CD74+ CXCR4) dependent inhibition of macrophages in metastatic papillary thyroid carcinoma

W Chen, X Yu, H Li, S Yuan, Y Fu, H Hu, F Liu, Y Zhang… - Oral Oncology, 2024 - Elsevier
Background The mechanism promoting papillary thyroid carcinoma (PTC) metastasis
remains unclear. We aimed to investigate the potential metastatic mechanisms at a single …

[HTML][HTML] PARP1 Characterization as a Potential Biomarker for BCR::ABL1 p190+ Acute Lymphoblastic Leukemia

CB Machado, EL da Silva, WAS Ferreira… - Cancers, 2023 - mdpi.com
Simple Summary Acute lymphoblastic leukemia (ALL) is the most common childhood cancer
and the presence of BCR:: ABL1 fusion in p190 isoform is a marker for worse prognosis …

[HTML][HTML] Single-cell RNA-Seq Elucidates the Crosstalk Between Cancer Stem Cells and the Tumor Microenvironment in Hepatocellular Carcinoma

S Lin, D Li, Y Yang, M Yu, R Zhao, J Li, L Peng - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Background: The challenge of systemic treatment for hepatocellular carcinoma (HCC) stems
from the development of drug resistance, primarily driven by the interplay between cancer …