Research progress in the pharmacological activities, toxicities, and pharmacokinetics of sophoridine and its derivatives

Q Tang, Y Liu, X Peng, B Wang, F Luan… - Drug Design …, 2023 - Taylor & Francis
Sophoridine is a natural quinolizidine alkaloid and a bioactive ingredient that can be
isolated and identified from certain herbs, including Sophora flavescens Alt, Sophora …

Sophoridine suppresses herpes simplex virus type 1 infection by blocking the activation of cellular PI3K/Akt and p38 MAPK pathways

Q Tang, F Luan, A Yuan, J Sun, Z Rao… - Frontiers in …, 2022 - frontiersin.org
Herpes simplex virus type 1 (HSV-1) is a ubiquitous and important human pathogen capable
of causing significant clinical diseases ranging from skin damage to encephalitis, particularly …

Phytotoxic Activity of Alkaloids in the Desert Plant Sophora alopecuroides

L Lei, Y Zhao, K Shi, Y Liu, Y Hu, H Shao - Toxins, 2021 - mdpi.com
Sophora alopecuroides is known to produce relatively large amounts of alkaloids; however,
their ecological consequences remain unclear. In this study, we evaluated the allelopathic …

Simulation analysis and physiological and biochemical evaluation of Sophora flavescens aboveground against aphids using network pharmacology

C Guo, B Zhou, Y Liu, H Niu, L Lv, M Li - Pesticide Biochemistry and …, 2023 - Elsevier
Pests cause substantial damage to human environments; therefore, studying insecticidal
mechanisms is crucial for improving pest control. However, the use of chemical pesticides …