Candida albicans Biofilms and Human Disease

CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

[PDF][PDF] Microbial persistence and the road to drug resistance

NR Cohen, MA Lobritz, JJ Collins - Cell host & microbe, 2013 - cell.com
Microbial drug persistence is a widespread phenomenon in which a subpopulation of
microorganisms is able to survive antimicrobial treatment without acquiring resistance …

Fungal biofilm resistance

G Ramage, R Rajendran, L Sherry… - International journal of …, 2012 - Wiley Online Library
Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

[HTML][HTML] Candida Species Biofilms' Antifungal Resistance

S Silva, CF Rodrigues, D Araújo, ME Rodrigues… - Journal of Fungi, 2017 - mdpi.com
Candida infections (candidiasis) are the most prevalent opportunistic fungal infection on
humans and, as such, a major public health problem. In recent decades, candidiasis has …

Fungal biofilms, drug resistance, and recurrent infection

JV Desai, AP Mitchell… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
A biofilm is a surface-associated microbial community. Diverse fungi are capable of biofilm
growth. The significance of this growth form for infection biology is that biofilm formation on …

Probiotic lactobacilli inhibit early stages of Candida albicans biofilm development by reducing their growth, cell adhesion, and filamentation

VH Matsubara, Y Wang, H Bandara, MPA Mayer… - Applied microbiology …, 2016 - Springer
We evaluated the inhibitory effects of the probiotic Lactobacillus species on different phases
of Candida albicans biofilm development. Quantification of biofilm growth and ultrastructural …

Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms

N Delattin, BPA Cammue, K Thevissen - Future medicinal chemistry, 2014 - Future Science
Invasive fungal infections are associated with very high mortality rates ranging from 20–90%
for opportunistic fungal pathogens such as Candida albicans, Cryptococcus neoformans …

[HTML][HTML] Drug resistance in eukaryotic microorganisms

AH Fairlamb, NAR Gow, KR Matthews… - Nature microbiology, 2016 - nature.com
Eukaryotic microbial pathogens are major contributors to illness and death globally.
Although much of their impact can be controlled by drug therapy as with prokaryotic …

[HTML][HTML] Influence of laboratory culture media on in vitro growth, adhesion, and biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus

G Wijesinghe, A Dilhari, B Gayani… - Medical Principles and …, 2019 - karger.com
Objective: Pseudomonas aeruginosa and Staphylococcus aureus dual-species biofilm
infections are notoriously difficult to manage. This study aimed at investigating the influence …

[HTML][HTML] Divergent Approaches to Virulence in C. albicans and C. glabrata: Two Sides of the Same Coin

M Galocha, P Pais, M Cavalheiro, D Pereira… - International journal of …, 2019 - mdpi.com
Candida albicans and Candida glabrata are the two most prevalent etiologic agents of
candidiasis worldwide. Although both are recognized as pathogenic, their choice of …