[PDF][PDF] Biofilms and antifungal resistance

EP Fox, SD Singh-Babak, N Hartooni… - … : From Genomics to …, 2015 - researchgate.net
Infections caused by pathogenic fungi are a significant medical problem, as they are able to
disseminate to nearly every organ of the human body and there are few classes of antifungal …

Pitfalls associated with discriminating mixed-species biofilms by flow cytometry

T Grainha, AP Magalhães, LDR Melo, MO Pereira - Antibiotics, 2020 - mdpi.com
Since biofilms are ubiquitous in different settings and act as sources of disease for humans,
reliable methods to characterize and quantify these microbial communities are required …

Cell wall-modifying antifungal drugs

DS Perlin - The Fungal Cell Wall: An Armour and a Weapon for …, 2020 - Springer
Antifungal therapy is a critical component of patient management for invasive fungal
diseases. Yet, therapeutic choices are limited as only a few drug classes are available to …

Glyceraldehyde 3-Phosphate Dehydrogenase on the Surface of Candida albicans and Nakaseomyces glabratus Cells—A Moonlighting Protein That Binds Human …

A Bednarek, D Satala, M Zawrotniak, AH Nobbs… - International Journal of …, 2024 - mdpi.com
Candida albicans and other closely related pathogenic yeast-like fungi carry on their surface
numerous loosely adsorbed “moonlighting proteins”—proteins that play evolutionarily …

Hydroalcoholic extract of Myrcia bella loaded into a microemulsion system: a study of antifungal and mutagenic potential

GD Marena, L Girotto, LL Saldanha… - Planta …, 2022 - thieme-connect.com
Myrcia bella is a medicinal plant used for the treatment of diabetes, hemorrhages, and
hypertension in Brazilian folk medicine. Considering that plant extracts are attractive sources …

The Eagle-like effect of echinocandins: what's in a name?

K Vanstraelen, K Lagrou, J Maertens… - Expert review of anti …, 2013 - Taylor & Francis
Despite several years of research, a lot of questions remain about the paradoxical
attenuation of echinocandin activity against Candida and Aspergillus species at certain drug …

Influence of culture conditions for clinically isolated non-albicans Candida biofilm formation

Y Tan, M Leonhard, S Ma… - Journal of microbiological …, 2016 - Elsevier
Non-albicans Candida species have been isolated in increasing numbers in patients.
Moreover, they are adept at forming biofilms. This study analyzed biofilm formation of …

High-content phenotypic screenings to identify inhibitors of Candida albicans biofilm formation and filamentation

CG Pierce, SP Saville, JL Lopez-Ribot - Pathogens and disease, 2014 - academic.oup.com
Candida species represent the main cause of opportunistic fungal infections worldwide, and
Candida albicans remains the most common etiological agent of candidiasis, now the third …

FLO8 deletion leads to decreased adhesion and virulence with downregulated expression of EPA1, EPA6, and EPA7 in Candida glabrata

JT Zhao, KZ Chen, JY Liu, WH Li, YZ Wang… - Brazilian Journal of …, 2022 - Springer
Abstract Background The Candida glabrata does not develop into a pathogenic hiphal form;
however, it has become the second most common pathogen of fungal infections in humans …

Thymoquinone Antifungal Activity against Candida glabrata Oral Isolates from Patients in Intensive Care Units—An In Vitro Study

N Nouri, SR Mohammadi, J Beardsley, P Aslani… - Metabolites, 2023 - mdpi.com
The number of Candida spp. infections and drug resistance are dramatically increasing
worldwide, particularly among immunosuppressed patients, and it is urgent to find novel …