Lipids and lipid mediators associated with the risk and pathology of ischemic stroke

A Kloska, M Malinowska, M Gabig-Cimińska… - International Journal of …, 2020 - mdpi.com
Stroke is a severe neurological disorder in humans that results from an interruption of the
blood supply to the brain. Worldwide, stoke affects over 100 million people each year and is …

The beneficial effects of HMG-CoA reductase inhibitors in the processes of neurodegeneration

SS Saeedi Saravi, SS Saeedi Saravi, A Arefidoust… - Metabolic brain …, 2017 - Springer
Statins, cholesterol lowering drugs, have been demonstrated to exert beneficial effects in
other conditions such as primary and progressing neurodegenerative diseases beyond their …

The benefits and risks of statin therapy in ischemic stroke: a review of the literature

W Zhao, ZJ Xiao, SP Zhao - Neurology India, 2019 - journals.lww.com
Statins are effective cholesterol-lowering drugs for reducing the risks of mortality and
morbidity of cardiovascular diseases. Increasing evidence has shown that statin use is …

[HTML][HTML] Effect and safety of rosuvastatin in acute ischemic stroke

JH Heo, D Song, HS Nam, EY Kim, YD Kim… - Journal of …, 2016 - ncbi.nlm.nih.gov
Background and Purpose The benefit of statins in acute stroke remains uncertain. Statins
may prevent stroke recurrence during the acute stage of stroke via pleiotropic effects …

The efficacy and safety of high-dose statins in acute phase of ischemic stroke and transient ischemic attack: a systematic review

J Fang, E Wang, W Wang, Y Liu, G Cheng - Internal and Emergency …, 2017 - Springer
Inconsistent findings in the studies have been observed concerning the higher dose of
statins use in the acute phase of ischemic stroke and transient ischemic attack (TIA) …

A review on the efficacy and safety of lipid-lowering drugs in neurodegenerative disease

A Rajabian, AP McCloskey, T Jamialahmadi… - Reviews in the …, 2023 - degruyter.com
There is a train of thought that lipid therapies may delay or limit the impact of neuronal loss
and poor patient outcomes of neurodegenerative diseases (NDDs). A variety of medicines …

The LDL-receptor and its molecular properties: From theory to novel biochemical and pharmacological approaches in reducing LDL-cholesterol

D Petroglou, I Kanellos, C Savopoulos… - Current Medicinal …, 2020 - ingentaconnect.com
Background: The Low-Density Lipoprotein (LDL) Receptor (LDL-R) is a transmembrane
protein playing a crucial role in effective lipid homeostasis. Various therapeutic agents have …

Low-dose statin pretreatment reduces stroke severity and improves functional outcomes

S Dong, J Guo, J Fang, Y Hong, S Cui, L He - Journal of Neurology, 2019 - Springer
Objectives Pre-stroke statin use reduces stroke severity and improves functional outcomes;
however, whether low-dose statins as a primary preventive measure have similar effects on …

Association of apolipoprotein E genotype with outcome in hospitalized ischemic stroke patients

Y Zhang, S Liu, W Yue, Z Shi, Y Guan, M Li, Y Ji, X Li - Medicine, 2017 - journals.lww.com
Association of apolipoprotein E genotype with outcome in hos... : Medicine Association of
apolipoprotein E genotype with outcome in hospitalized ischemic stroke patients : Medicine Log …

Management of dyslipidaemia for the prevention of stroke: clinical practice recommendations from the Lipid Association of India

R Puri, V Mehta, SS Iyengar… - Current Vascular …, 2022 - ingentaconnect.com
Stroke is the second most common cause of death worldwide. The rates of stroke are
increasing in less affluent countries predominantly because of a high prevalence of …