Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems

M Danaei, M Dehghankhold, S Ataei… - Pharmaceutics, 2018 - mdpi.com
Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to
enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both …

PLGA-based nanoparticles as cancer drug delivery systems

FS Tabatabaei Mirakabad, K Nejati-Koshki… - Asian Pacific Journal …, 2014 - koreascience.kr
Poly (lactic-co-glycolic acid)(PLGA) is one of the most effective biodegradable polymeric
nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems …

Functionalized reduced graphene oxide as a versatile tool for cancer therapy

BS Dash, G Jose, YJ Lu, JP Chen - International journal of molecular …, 2021 - mdpi.com
Cancer is one of the deadliest diseases in human history with extremely poor prognosis.
Although many traditional therapeutic modalities—such as surgery, chemotherapy, and …

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

S Wang, R Su, S Nie, M Sun, J Zhang, D Wu… - The Journal of nutritional …, 2014 - Elsevier
Nanotechnology is an innovative approach that has potential applications in nutraceutical
research. Phytochemicals have promising potential for maintaining and promoting health, as …

Tetrandrine: a review of its anticancer potentials, clinical settings, pharmacokinetics and drug delivery systems

F Luan, X He, N Zeng - Journal of Pharmacy and Pharmacology, 2020 - academic.oup.com
Objectives Tetrandrine, a natural bisbenzylisoquinoline alkaloid, possesses promising
anticancer activities on diverse tumours. This review provides systematically organized …

Methylene blue-loaded niosome: preparation, physicochemical characterization, and in vivo wound healing assessment

A Farmoudeh, J Akbari, M Saeedi, M Ghasemi… - Drug delivery and …, 2020 - Springer
Following skin injury, the overproduction of reactive oxygen species (ROS) during the
inflammatory phase can cause tissue damage and delay in wound healing. Methylene blue …

Drug-loaded nanocarriers: passive targeting and crossing of biological barriers

JM Rabanel, V Aoun, I Elkin… - Current medicinal …, 2012 - ingentaconnect.com
Poor bioavailability and poor pharmacokinetic characteristics are some of the leading
causes of drug development failure. Therefore, poorly-soluble drugs, fragile proteins or …

Fabrication of cellulose nanocrystals as potential anticancer drug delivery systems for colorectal cancer treatment

M Yusefi, MLK Soon, SY Teow, EI Monchouguy… - International Journal of …, 2022 - Elsevier
Polysaccharide nanocrystals have great potential to be used as improved drug carriers due
to their low cost, high biodegradability, and biocompatibility. This study reports the synthesis …

[HTML][HTML] Systemic delivery to central nervous system by engineered PLGA nanoparticles

Q Cai, L Wang, G Deng, J Liu, Q Chen… - American journal of …, 2016 - ncbi.nlm.nih.gov
Neurological disorders are an important global public health problem, but pharmaceutical
treatments are limited due to drug access to the central nervous system being restricted by …

Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer

A Gianella, PA Jarzyna, V Mani, S Ramachandran… - ACS …, 2011 - ACS Publications
Nanoparticle applications in medicine have seen a tremendous growth in the past decade.
In addition to their drug targeting application and their ability to improve bioavailability of …