HTLV-1-associated myelopathy/tropical spastic paraparesis

CRM Bangham, A Araujo, Y Yamano… - Nature reviews Disease …, 2015 - nature.com
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

[HTML][HTML] An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) focusing on clinical and laboratory …

J Yamauchi, N Araya, N Yagishita, T Sato… - Pharmacology & …, 2021 - Elsevier
Human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a rare inflammatory disease causing unremitting and progressive …

Modulating CCR2 and CCL2 at the blood–brain barrier: relevance for multiple sclerosis pathogenesis

D Mahad, MK Callahan, KA Williams, EE Ubogu… - Brain, 2006 - academic.oup.com
Chemokines and chemokine receptors play a key role in the transmigration of leucocytes
across the blood–brain barrier (BBB). CCR2 is the major receptor for CCL2, a potent …

CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis

T Sato, A Coler-Reilly, A Utsunomiya… - PLoS neglected …, 2013 - journals.plos.org
Background Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical
spastic paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. Since the …

Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy

S Tattermusch, JA Skinner, D Chaussabel… - PLoS …, 2012 - journals.plos.org
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that persists lifelong in the host.
In∼ 4% of infected people, HTLV-1 causes a chronic disabling neuroinflammatory disease …

Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy

H Ando, T Sato, U Tomaru, M Yoshida, A Utsunomiya… - Brain, 2013 - academic.oup.com
Human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a rare neurodegenerative disease characterized by chronic inflammation in …

[HTML][HTML] HTLV-1 induces an inflammatory CD4+ CD8+ T cell population in HTLV-1–associated myelopathy

AK Maher, A Aristodemou, N Giang, Y Tanaka… - JCI insight, 2024 - ncbi.nlm.nih.gov
Human T cell leukemia virus type 1 (HTLV-1) is a retrovirus that infects at least 5 million to
10 million people worldwide (1–3). Although the majority of HTLV-1–infected individuals …

Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Y Enose-Akahata, S Jacobson - Retrovirology, 2019 - Springer
Human T cell lymphotropic virus 1 (HTLV-1) is a human retrovirus and infects approximately
10–20 million people worldwide. While the majority of infected people are asymptomatic …

The Role of Chemokines in the Pathogenesis of HTLV-1

R Zargari, M Mahdifar, A Mohammadi… - Frontiers in …, 2020 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is a human retrovirus that is associated with
two main diseases: HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Distinct CSF cytokine/chemokine profiles in atopic myelitis and other causes of myelitis

M Tanaka, T Matsushita, T Tateishi, H Ochi, Y Kawano… - Neurology, 2008 - AAN Enterprises
Background: We reported the emergence of a distinct myelitis in patients with atopic
diathesis (atopic myelitis [AM]) by a nationwide survey throughout Japan. Similar cases have …