CXCL13/CXCR5 signaling axis in cancer
The tumor microenvironment comprises stromal and tumor cells which interact with each
other through complex cross-talks that are mediated by a variety of growth factors, cytokines …
other through complex cross-talks that are mediated by a variety of growth factors, cytokines …
[HTML][HTML] Potential role of CXCL13/CXCR5 signaling in immune checkpoint inhibitor treatment in cancer
CH Hsieh, CZ Jian, LI Lin, GS Low, PY Ou, C Hsu… - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy is currently the backbone of new drug treatments for many
cancer patients. CXC chemokine ligand 13 (CXCL13) is an important factor involved in …
cancer patients. CXC chemokine ligand 13 (CXCL13) is an important factor involved in …
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis
Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million
people worldwide, with increasing incidence in westernized countries,. To elucidate the …
people worldwide, with increasing incidence in westernized countries,. To elucidate the …
Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice
Abstract Approximately 15–40% of all cancers develop metastases in the central nervous
system (CNS), yet few therapeutic options exist to treat them. Cancer therapies based on …
system (CNS), yet few therapeutic options exist to treat them. Cancer therapies based on …
[HTML][HTML] CXCL13 in cancer and other diseases: biological functions, clinical significance, and therapeutic opportunities
SH Gao, SZ Liu, GZ Wang, GB Zhou - Life, 2021 - mdpi.com
The development of cancer is a multistep and complex process involving interactions
between tumor cells and the tumor microenvironment (TME). CXC chemokine ligand 13 …
between tumor cells and the tumor microenvironment (TME). CXC chemokine ligand 13 …
[HTML][HTML] Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region
Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously
identified human leukocyte antigen (HLA) gene variants. To identify additional FL …
identified human leukocyte antigen (HLA) gene variants. To identify additional FL …
Chemokines orchestrate tumor cells and the microenvironment to achieve metastatic heterogeneity
Chemokines, a subfamily of the cell cytokines, are low molecular weight proteins known to
induce chemotaxis in leukocytes in response to inflammatory and pathogenic signals. A …
induce chemotaxis in leukocytes in response to inflammatory and pathogenic signals. A …
The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma
RL Boddicker, NS Kip, X Xing, Y Zeng… - Blood, The Journal …, 2015 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) are generally aggressive non-Hodgkin lymphomas
with poor overall survival rates following standard therapy. One-third of PTCLs express …
with poor overall survival rates following standard therapy. One-third of PTCLs express …
Cohort profile: the lymphoma specialized program of research excellence (SPORE) molecular epidemiology resource (MER) cohort study
In 2016, an estimated 70 580 people in the USA will have been diagnosed and 20150 will
have died from non-Hodgkin lymphoma (NHL). 1 NHL incidence rates increased over the …
have died from non-Hodgkin lymphoma (NHL). 1 NHL incidence rates increased over the …
Genetics of systemic lupus erythematosus and Sjögren's syndrome: an update
M Teruel, ME Alarcón-Riquelme - Current opinion in …, 2016 - journals.lww.com
SLE and Sjögren's syndrome are two closely related systemic autoimmune diseases that
share multiple clinical and molecular aspects, including a significant number of susceptibility …
share multiple clinical and molecular aspects, including a significant number of susceptibility …