Viral hepatitis, cholesterol metabolism, and cholesterol-lowering natural compounds
JW Liou, H Mani, JH Yen - International Journal of Molecular Sciences, 2022 - mdpi.com
Hepatitis is defined as inflammation of the liver; it can be acute or chronic. In chronic cases,
the prolonged inflammation gradually damages the liver, resulting in liver fibrosis, cirrhosis …
the prolonged inflammation gradually damages the liver, resulting in liver fibrosis, cirrhosis …
Advances in nanoparticle-based mRNA delivery for liver cancer and liver-associated infectious diseases
The liver is a vital organ that functions to detoxify the body. Liver cancer and infectious
diseases such as influenza and malaria can fatally compromise liver function. mRNA …
diseases such as influenza and malaria can fatally compromise liver function. mRNA …
Mouse Models for Human Herpesviruses
I Kutle, A Dittrich, D Wirth - Pathogens, 2023 - mdpi.com
More than one hundred herpesviruses have been isolated from different species so far, with
nine infecting humans. Infections with herpesviruses are characterized by life-long latency …
nine infecting humans. Infections with herpesviruses are characterized by life-long latency …
Overview of the development of HBV small molecule inhibitors
H Yang, W Yao, J Yang - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract Like tuberculosis and Acquired Immune Deficiency Syndrome (AIDS), hepatitis B is
a globally recognized major public health threat. Although there are many small-molecule …
a globally recognized major public health threat. Although there are many small-molecule …
Hepatic manifestations of systemic diseases
HC Gonzalez, SC Gordon - Medical Clinics, 2023 - medical.theclinics.com
Worldwide, tuberculosis (TB)—caused by Mycobacterium tuberculosis—accounts for
approximately 10 million infections and 1.5 million deaths each year (Table 1). 1 In the …
approximately 10 million infections and 1.5 million deaths each year (Table 1). 1 In the …
Non-hepatotropic viral hepatitis and its causative pathogens: The ongoing need for monitoring in children with severe acute hepatitis of unknown etiology
R Wang, Z Xie - Pediatric Investigation, 2022 - mednexus.org
As of June 22, 2022, 920 probable cases of severe acute hepatitis of unknown etiology had
been reported in 33 countries. 1 The numbers of reported cases were the highest in the …
been reported in 33 countries. 1 The numbers of reported cases were the highest in the …
Integrative analyses of potential biomarkers and pathways for non-obstructive azoospermia
Y Zhong, X Chen, J Zhao, H Deng, X Li, Z Xie… - Frontiers in …, 2022 - frontiersin.org
Background: Non-obstructive azoospermia (NOA) is the most severe form of male infertility.
Currently, the molecular mechanisms underlying NOA pathology have not yet been …
Currently, the molecular mechanisms underlying NOA pathology have not yet been …
The intersection of virus infection and liver disease: A comprehensive review of pathogenesis, diagnosis, and treatment
M Ren, C Lu, M Zhou, X Jiang, X Li… - WIREs Mechanisms of …, 2024 - Wiley Online Library
Liver disease represents a significant global burden, placing individuals at a heightened risk
of developing cirrhosis and liver cancer. Viral infections act as a primary cause of liver …
of developing cirrhosis and liver cancer. Viral infections act as a primary cause of liver …
Exploring Peripheral Blood-Derived Extracellular Vesicles as Biomarkers: Implications for Chronic Chagas Disease with Viral Infection or Transplantation
RP Madeira, P Meneghetti, N Lozano, GM Namiyama… - Microorganisms, 2024 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer envelopes that encapsulate cell-specific cargo,
rendering them promising biomarkers for diverse diseases. Chagas disease, caused by the …
rendering them promising biomarkers for diverse diseases. Chagas disease, caused by the …
[HTML][HTML] Granulomatous liver diseases
M Mironova, H Gopalakrishna, GR Franco… - Hepatology …, 2024 - journals.lww.com
A granuloma is a discrete collection of activated macrophages and other inflammatory cells.
Hepatic granulomas can be a manifestation of localized liver disease or be a part of a …
Hepatic granulomas can be a manifestation of localized liver disease or be a part of a …