The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABAA receptor alterations in the human …

M Glass, M Dragunow, RLM Faull - Neuroscience, 2000 - Elsevier
In order to investigate the sequence and pattern of neurodegeneration in Huntington's
disease, the distribution and density of cannabinoid CB1, dopamine D1 and D2, adenosine …

Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry

P Mailleux, JJ Vanderhaeghen - Neuroscience, 1992 - Elsevier
The neuronal distribution of cannabinoid receptor in the adult rat brain is reported,
combining receptor binding radioautography using the synthetic psychoactive cannabinoid …

Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum

JS Fink, DR Weaver, SA Rivkees, RA Peterfreund… - Molecular Brain …, 1992 - Elsevier
A cDNA fragment homologous to other G protein-coupled receptors was isolated from rat
brain using the PCR method and demonstrated to be abundantly expressed in striatum …

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

JH Baik, R Picetti, A Saiardi, G Thiriet, A Dierich… - Nature, 1995 - nature.com
DOPAMINERGIC neuronal pathways arise from mesencephalic nuclei and project axons to
the striatum, cortex, limbic system and hypothalamus1, 2. Through these pathways …

A novel neuronal messenger molecule in brain: the free radical, nitric oxide

TM Dawson, VL Dawson… - Annals of Neurology …, 1992 - Wiley Online Library
Understanding of the organization and function of a newly identified neuronal messenger
molecule, nitric oxide, has progressed rapidly. Nitric oxide synthase has been purified and …

The role of dopamine in drug abuse viewed from the perspective of its role in motivation

G Di Chiara - Drug and alcohol dependence, 1995 - Elsevier
Drugs of abuse share with conventional reinforcers the activation of specific neural
pathways in the CNS that are the substrate of their motivational properties. Dopamine is …

Distribution, biochemistry and function of striatal adenosine A2A receptors

P Svenningsson, C Le Moine, G Fisone… - Progress in …, 1999 - Elsevier
It is well known that the nucleoside adenosine exerts a modulatory influence in the central
nervous system by activating G protein coupled receptors. Adenosine A2A receptors, the …

Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy

KKL Yung, JP Bolam, AD Smith, SM Hersch, BJ Ciliax… - Neuroscience, 1995 - Elsevier
The modulatory actions of dopamine on the flow of cortical information through the basal
ganglia are mediated mainly through two subtypes of receptors, the D1 and D2 receptors. In …

Chapter II The basal ganglia

CR Gerfen, CJ Wilson - Handbook of chemical neuroanatomy, 1996 - Elsevier
Publisher Summary The basal ganglia are a major neural system that receive cortical inputs,
process these inputs, and feed them back to the cortex via connections through the midbrain …

D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct …

C Le Moine, B Bloch - Journal of Comparative Neurology, 1995 - Wiley Online Library
The postsynaptic effects of dopamine in the striatum are mediated mainly by receptors
encoded by D1, D2, and D3 dopamine receptor genes. The D1 and D2 genes are the most …