The flow of cortical information through the basal ganglia occurs through the so‐called
'direct pathway'and 'indirect pathways'. The object of the present work was to attempt to …

Drugs that stimulate dopamine and glutamate receptors have been shown to induce the
expression of AP-1 proteins (such as c-Fos and c-Jun) in the striatum and to induce binding …

The basal ganglia comprise a subcortical brain system through which the cerebral cortex
affects behavior. The principal input structure is the striatum, whose GABAergic medium …

In order to investigate the role of adenosine A2A receptor blockade on dopamine-mediated
motor responses, contralateral turning behaviour and expression of the early-gene c-fos was …

Studies of signal transduction carried out over the past decade have demonstrated a central
role for the DARPP-32 Ždopamine-and cAMP-regulated phosphoprotein, of ap-. Ž. parent M …

The localization of D1 and D2 dopamine receptors to striatal projection neuron types has
been controversial, with some data favoring segregation of D1 to direct pathway neurons …

In the infant and adult human basal ganglia, the finding of mRNA exclusively in the striatal
medium-sized neurons together with the detection of [3 H] CP55, 940 binding sites in the …

Psychomotor stimulants such as cocaine alter gene expression in neurons of the striatum.
Whereas many of these effects are mediated by D1 dopamine receptors, the involvement of …

For over a decade it has been generally assumed that all the pharmacological and
biochemical actions of dopamine within the central nervous system and periphery were …

We report a patient with severe axial tardive dystonia who has had dramatic improvement for
4 years after treatment with the atypical antipsychotic drug clozapine (625 mg/day) …