LOX‐1, OxLDL, and atherosclerosis

A Pirillo, GD Norata, AL Catapano - Mediators of inflammation, 2013 - Wiley Online Library
Oxidized low‐density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation
and progression by several mechanisms, including the induction of endothelial cell …

The evidence for saturated fat and for sugar related to coronary heart disease

JJ DiNicolantonio, SC Lucan, JH O'Keefe - Progress in cardiovascular …, 2016 - Elsevier
Dietary guidelines continue to recommend restricting intake of saturated fats. This
recommendation follows largely from the observation that saturated fats can raise levels of …

[HTML][HTML] LOX-1: regulation, signaling and its role in atherosclerosis

AJ Kattoor, A Goel, JL Mehta - Antioxidants, 2019 - mdpi.com
Atherosclerosis has long been known to be a chronic inflammatory disease. In addition,
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …

Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

A Trpkovic, I Resanovic, J Stanimirovic… - Critical reviews in …, 2015 - Taylor & Francis
Atherosclerosis is a life-long illness that begins with risk factors, which in turn contribute to
the development of subclinical disease, followed by the establishment of overt …

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents

R Lordan, A Tsoupras, I Zabetakis - Blood reviews, 2021 - Elsevier
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

[HTML][HTML] CD36, a scavenger receptor implicated in atherosclerosis

YM Park - Experimental & molecular medicine, 2014 - nature.com
CD36 is a membrane glycoprotein that is present on various types of cells, including
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …

[HTML][HTML] Platelets in inflammation and atherogenesis

HM Nording, P Seizer, HF Langer - Frontiers in immunology, 2015 - frontiersin.org
Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …

[HTML][HTML] Platelet-derived CXCL12 regulates monocyte function, survival, differentiation into macrophages and foam cells through differential involvement of CXCR4 …

M Chatterjee, SNI von Ungern-Sternberg, P Seizer… - Cell death & …, 2015 - nature.com
Platelets store and release CXCL12 (SDF-1), which governs differentiation of hematopoietic
progenitors into either endothelial or macrophage-foam cells. CXCL12 ligates CXCR4 and …

Platelets mediate oxidized low-density lipoprotein–induced monocyte extravasation and foam cell formation

S Badrnya, WC Schrottmaier, JB Kral… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—A growing body of evidence indicates that platelets contribute to the onset and
progression of atherosclerosis by modulating immune responses. We aimed to elucidate the …

[HTML][HTML] Targeting platelet in atherosclerosis plaque formation: current knowledge and future perspectives

L Wang, C Tang - International journal of molecular sciences, 2020 - mdpi.com
Besides their role in hemostasis and thrombosis, it has become increasingly clear that
platelets are also involved in many other pathological processes of the vascular system …