LOX‐1, OxLDL, and atherosclerosis
Oxidized low‐density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation
and progression by several mechanisms, including the induction of endothelial cell …
and progression by several mechanisms, including the induction of endothelial cell …
The evidence for saturated fat and for sugar related to coronary heart disease
JJ DiNicolantonio, SC Lucan, JH O'Keefe - Progress in cardiovascular …, 2016 - Elsevier
Dietary guidelines continue to recommend restricting intake of saturated fats. This
recommendation follows largely from the observation that saturated fats can raise levels of …
recommendation follows largely from the observation that saturated fats can raise levels of …
[HTML][HTML] LOX-1: regulation, signaling and its role in atherosclerosis
Atherosclerosis has long been known to be a chronic inflammatory disease. In addition,
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …
Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases
A Trpkovic, I Resanovic, J Stanimirovic… - Critical reviews in …, 2015 - Taylor & Francis
Atherosclerosis is a life-long illness that begins with risk factors, which in turn contribute to
the development of subclinical disease, followed by the establishment of overt …
the development of subclinical disease, followed by the establishment of overt …
Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …
[HTML][HTML] CD36, a scavenger receptor implicated in atherosclerosis
YM Park - Experimental & molecular medicine, 2014 - nature.com
CD36 is a membrane glycoprotein that is present on various types of cells, including
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …
[HTML][HTML] Platelets in inflammation and atherogenesis
HM Nording, P Seizer, HF Langer - Frontiers in immunology, 2015 - frontiersin.org
Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …
underestimated role as an immune cell in various circumstances. This review outlines …
[HTML][HTML] Platelet-derived CXCL12 regulates monocyte function, survival, differentiation into macrophages and foam cells through differential involvement of CXCR4 …
M Chatterjee, SNI von Ungern-Sternberg, P Seizer… - Cell death & …, 2015 - nature.com
Platelets store and release CXCL12 (SDF-1), which governs differentiation of hematopoietic
progenitors into either endothelial or macrophage-foam cells. CXCL12 ligates CXCR4 and …
progenitors into either endothelial or macrophage-foam cells. CXCL12 ligates CXCR4 and …
Platelets mediate oxidized low-density lipoprotein–induced monocyte extravasation and foam cell formation
S Badrnya, WC Schrottmaier, JB Kral… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—A growing body of evidence indicates that platelets contribute to the onset and
progression of atherosclerosis by modulating immune responses. We aimed to elucidate the …
progression of atherosclerosis by modulating immune responses. We aimed to elucidate the …
[HTML][HTML] Targeting platelet in atherosclerosis plaque formation: current knowledge and future perspectives
L Wang, C Tang - International journal of molecular sciences, 2020 - mdpi.com
Besides their role in hemostasis and thrombosis, it has become increasingly clear that
platelets are also involved in many other pathological processes of the vascular system …
platelets are also involved in many other pathological processes of the vascular system …