Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …
heterogeneity of this disease presents a big challenge in its therapeutic management …
The mechanism of DNA methylation and miRNA in breast cancer
L Ma, C Li, H Yin, J Huang, S Yu, J Zhao… - International Journal of …, 2023 - mdpi.com
Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …
Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway
M Tufail, JJ Hu, J Liang, CY He, WD Wan… - Journal of Translational …, 2024 - Springer
Breast cancer (BC) is a multifaceted disease characterized by distinct molecular subtypes
and varying responses to treatment. In BC, the phosphatidylinositol 3-kinase (PI3K) pathway …
and varying responses to treatment. In BC, the phosphatidylinositol 3-kinase (PI3K) pathway …
Dual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer
Introduction The resistance to chemotherapy is a significant hurdle in breast cancer
treatment, prompting the exploration of innovative strategies. This review discusses the …
treatment, prompting the exploration of innovative strategies. This review discusses the …
Oxypalmatine regulates proliferation and apoptosis of breast cancer cells by inhibiting PI3K/AKT signaling and its efficacy against breast cancer organoids
X Lin, D Chen, X Chu, L Luo, Z Liu, J Chen - Phytomedicine, 2023 - Elsevier
Background Breast cancer (BC) is known as the most common cancer in women.
Discovering novel and effective drugs is a priority for the treatment of BC. Oxypalmatine …
Discovering novel and effective drugs is a priority for the treatment of BC. Oxypalmatine …
Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity
MG Salem, SAA El-Ata, EH Elsayed, SN Mali… - RSC …, 2023 - pubs.rsc.org
Breast cancer is a global health concern, with increasing disease burden and disparities in
access to healthcare. Late diagnosis and limited treatment options in underserved areas …
access to healthcare. Late diagnosis and limited treatment options in underserved areas …
Hypophyllanthin and Phyllanthin from Phyllanthus niruri Synergize Doxorubicin Anticancer Properties against Resistant Breast Cancer Cells
OE Abdel-Sattar, RM Allam, AM Al-Abd… - ACS …, 2023 - ACS Publications
Doxorubicin (DOX) is a cornerstone chemotherapeutic agent for the treatment of several
malignancies such as breast cancer; however, its activity is ameliorated by the development …
malignancies such as breast cancer; however, its activity is ameliorated by the development …
Treatments Targeting the Androgen Receptor and Its Splice Variants in Breast Cancer
AH Tien, MD Sadar - International Journal of Molecular Sciences, 2024 - mdpi.com
Breast cancer is a major cause of death worldwide. The complexity of endocrine regulation
in breast cancer may allow the cancer cells to escape from a particular treatment and result …
in breast cancer may allow the cancer cells to escape from a particular treatment and result …
DNA repair pathways in breast cancer: from mechanisms to clinical applications
M Tufail - Breast Cancer Research and Treatment, 2023 - Springer
Background Breast cancer (BC) is a complex disease with various subtypes and genetic
alterations that impact DNA repair pathways. Understanding these pathways is essential for …
alterations that impact DNA repair pathways. Understanding these pathways is essential for …
The current advances of lncRNAs in breast cancer immunobiology research
MA Fonseca-Montaño, KI Vázquez-Santillán… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is the most frequently diagnosed malignancy and the leading cause of cancer-
related death in women worldwide. Breast cancer development and progression are mainly …
related death in women worldwide. Breast cancer development and progression are mainly …