Bioactivity of dietary polyphenols: The role of metabolites

SV Luca, I Macovei, A Bujor, A Miron… - Critical reviews in …, 2020 - Taylor & Francis
A polyphenol-rich diet protects against chronic pathologies by modulating numerous
physiological processes, such as cellular redox potential, enzymatic activity, cell proliferation …

Phytosomal curcumin: A review of pharmacokinetic, experimental and clinical studies

H Mirzaei, A Shakeri, B Rashidi, A Jalili… - Biomedicine & …, 2017 - Elsevier
Curcumin, a hydrophobic polyphenol, is the principal constituent extracted from dried
rhizomes of Curcuma longa L.(turmeric). Curcumin is known as a strong anti-oxidant and …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Exploring recent developments to improve antioxidant, anti-inflammatory and antimicrobial efficacy of curcumin: A review of new trends and future perspectives

Z Hussain, HE Thu, MW Amjad, F Hussain… - Materials science and …, 2017 - Elsevier
Curcumin derivatives have been well-documented due to their natural antioxidant,
antimicrobial and anti-inflammatory activities. Curcuminoids have also gained widespread …

Recent developments in curcumin and curcumin based polymeric materials for biomedical applications: A review

K Mahmood, KM Zia, M Zuber, M Salman… - International journal of …, 2015 - Elsevier
Turmeric (Curcuma longa) is a popular Indian spice that has been used for centuries in
herbal medicines for the treatment of a variety of ailments such as rheumatism, diabetic …

[HTML][HTML] Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

R Wilken, MS Veena, MB Wang, ES Srivatsan - Molecular cancer, 2011 - Springer
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant,
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …

Innovative preparation of curcumin for improved oral bioavailability

H Sasaki, Y Sunagawa, K Takahashi… - Biological and …, 2011 - jstage.jst.go.jp
MIN Curcumin powder was extracted from Indian turmeric by using alcohol. THERACURMIN
was prepared as follows; first, gum ghatti, mainly consists of polysaccharides, obtained from …

Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia

RE Carroll, RV Benya, DK Turgeon, S Vareed… - Cancer prevention …, 2011 - AACR
Curcumin is derived from the spice tumeric and has antiinflammatory and antineoplastic
effects in vitro and in animal models, including preventing aberrant crypt foci (ACF) and …

[HTML][HTML] Curcumin-and piperine-loaded emulsomes as combinational treatment approach enhance the anticancer activity of curcumin on HCT116 colorectal cancer …

ZB Bolat, Z Islek, BN Demir, EN Yilmaz… - … in bioengineering and …, 2020 - frontiersin.org
Combination chemotherapy, administrating two chemotherapeutic agents concurrently,
comes into prominence, as the heterogeneity or the level of the disease necessitates a …

Polyphenols and human health: a prospectus

F Visioli, CADL Lastra, C Andres-Lacueva… - Critical reviews in …, 2011 - Taylor & Francis
The lay press often heralds polyphenols as panacea for all sorts of diseases. The rationale
is that their antioxidant activity would prevent free radical damage to macromolecules …