During the past two decades, small-molecule kinase inhibitors have proven to be valuable in
the treatment of solid and haematological tumours. However, because of their oral …

Abstract Erlotinib (OSI-774), marketed by Genentech as Tarceva®, is anticancer drug
approved by US-FDA for the treatment of Non-Small Cell Lung Cancer (NSCLC) and …

Nintedanib is an oral small-molecule kinase inhibitor and first-line treatment for idiopathic
pulmonary fibrosis. Nintedanib is a substrate of the drug efflux transporter ABCB1. Green tea …

Herbs have been used as sustenance and medicine for a very long time, often in
conjunction with other prescribed medications. Even though they are thought to be natural …

Inter-ethnic differences in systemic exposure, efficacy and safety have been reported for
some small molecule tyrosine kinase inhibitors (smTKIs). This variability in response related …

Background Numerous studies have reported the association between tea intake and lung
diseases. However, the probable relationship between tea consumption on lung diseases …

Complex biomolecules present in their natural sources have been difficult to analyze using
traditional analytical approaches. Ultrahigh-performance liquid chromatography (UHPLC …

Background: Erlotinib is a selective epidermal growth factor receptor inhibitor that is used for
the treatment of non‐small cell lung cancer and pancreatic cancer. Its metabolism is mainly …

The purpose of this study was to evaluate the potential of micelle to change the
pharmacokinetics of quercetin (QUT), with a primary goal of enhancing its oral …

Purpose Antidepressants like the serotonin reuptake inhibitors (SRIs) are often used
concomitantly with tamoxifen (eg for treatment of depression). This may lead to an additional …