Optimization of the ocular treatment following organophosphate nerve agent insult

I Egoz, U Nili, E Grauer, A Gore - Toxicological Sciences, 2017 - academic.oup.com
Eye exposure to organophosphate (OP) irreversible acetylcholinesterase inhibitors, results
in long-term miosis and impaired visual function. The aim of this study was to find an …

The effects of repeated low-dose sarin exposure

TM Shih, SW Hulet, JH McDonough - Toxicology and applied …, 2006 - Elsevier
This project assessed the effects of repeated low-dose exposure of guinea pigs to the
organophosphorus nerve agent sarin. Animals were injected once a day, 5 days per week …

Efficacy of retigabine in ameliorating the brain insult following sarin exposure in the rat

A Gore, A Neufeld-Cohen, I Egoz, S Baranes… - Toxicology and Applied …, 2020 - Elsevier
Background Sarin is an irreversible organophosphate cholinesterase inhibitor. Following
toxic signs, an extensive long-term brain damage is often reported. Thus, we evaluated the …

[PDF][PDF] The pharmacokinetics of intraosseous atropine in hypovolemic swine

A Claessens, D Johnson - American journal of disaster medicine, 2015 - researchgate.net
Scanned Document Page 1 ORIGINAL ARTICLE The pharmacokinetics of intraosseous
atropine in hypovolemic swine Jonathan Yost, CRNA, MSN; Phillip Baldwin, CRNA, MSN; …

Chemical terrorism for the intensivist

JA Chalela, WT Burnett - Military medicine, 2012 - academic.oup.com
The use of chemical agents for terrorist attacks or military warfare is a major concern at the
present time. Chemical agents can cause significant morbidity, are relatively inexpensive …

Synergism between anticholinergic and oxime treatments against sarin-induced ocular insult in rats

A Gore, R Brandeis, I Egoz, J Turetz, U Nili… - Toxicological …, 2015 - academic.oup.com
Eye exposure to the extremely toxic organophosphorus sarin results in long-term miosis and
visual impairment. As current treatment using atropine or homatropine eye drops may lead …

Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats

A Gore, R Brandeis, I Egoz, D Peri, J Turetz… - Toxicological …, 2012 - academic.oup.com
Eye exposure to the organophosphorus (OP) irreversible acetylcholinesterase inhibitor sarin
results in long-term miosis and reduction in visual function. Anticholinergic drugs, such as …

Early diagnosis of nerve agent exposure with a mobile test kit and implications for medical countermeasures: a trigger to react

T Wille, S Djordjević, F Worek, H Thiermann… - BMJ Mil …, 2020 - militaryhealth.bmj.com
Recent uses of nerve agents underline the need of early diagnosis as trigger to react
(initiating medical countermeasures, avoiding cross-contamination). As organophosphorus …

Broad spectrum treatment for ocular insult induced by organophosphate chemical warfare agents

A Gore - Toxicological Sciences, 2020 - academic.oup.com
Warfare organophosphates nerve agents constitute one of the prime threats to mankind on
the battlefield and in the scenario of civilian terror. Exposure to organophosphate (OP) nerve …

[图书][B] Medical support in a chemical, biological, radiological, and nuclear contested environment

M Hanson, J Garrison, C Backus, LA Calderwood… - 2021 - airuniversity.af.edu
On a daily basis America's Warfighters rely on our Total Force Warrior Medics, which include
Air Force Active, Guard and Reserve medical professionals, to deliver on the promise of …