Targeting redox regulation and autophagy systems in cancer stem cells

SU Khan, S Rayees, P Sharma, F Malik - Clinical and Experimental …, 2023 - Springer
Cancer is a dysregulated cellular level pathological condition that results in tumor formation
followed by metastasis. In the heterogeneous tumor architecture, cancer stem cells (CSCs) …

[HTML][HTML] Immunotherapy for targeting cancer stem cells in hepatocellular carcinoma

X Dai, Y Guo, Y Hu, X Bao, X Zhu, Q Fu, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
The rapid development and remarkable success of checkpoint inhibitors have provided
significant breakthroughs in cancer treatment, including hepatocellular carcinoma (HCC) …

Stem cells under the influence of alcohol: effects of ethanol consumption on stem/progenitor cells

G Di Rocco, S Baldari, G Pani, G Toietta - Cellular and Molecular Life …, 2019 - Springer
Stem cells drive embryonic and fetal development. In several adult tissues, they retain the
ability to self-renew and differentiate into a variety of specialized cells, thus contributing to …

Precision medicine gains momentum: Novel 3D models and stem cell-based approaches in head and neck cancer

A Affolter, A Lammert, J Kern, C Scherl… - Frontiers in cell and …, 2021 - frontiersin.org
Despite the current progress in the development of new concepts of precision medicine for
head and neck squamous cell carcinoma (HNSCC), in particular targeted therapies and …

The individual and combined effects of alcohol consumption and cigarette smoking on site-specific cancer risk in a prospective cohort of 26,607 adults: results from …

B Viner, AM Barberio, TR Haig, CM Friedenreich… - Cancer Causes & …, 2019 - Springer
Purpose Alcohol consumption and cigarette smoking increase the risk of developing several
cancers. We examined the individual and synergistic effects of these modifiable lifestyle …

Ductal carcinoma in situ progression in dog model of breast cancer

SI Mohammed, S Utturkar, M Lee, HH Yang, Z Cui… - Cancers, 2020 - mdpi.com
The mechanisms that drive ductal carcinoma in situ (DCIS) progression to invasive cancer
are not clear. Studying DCIS progression in humans is challenging and not ethical, thus …

Biochemical mechanisms associating alcohol use disorders with cancers

FD Rodriguez, R Coveñas - Cancers, 2021 - mdpi.com
Simple Summary Of all yearly deaths attributable to alcohol consumption globally,
approximately 12% are due to cancers, representing approximately 0.4 million deceased …

Epithelial to mesenchymal transition is involved in ethanol promoted hepatocellular carcinoma cells metastasis and stemness

D Chen, D Yu, X Wang, Y Liu, Y He… - Molecular …, 2018 - Wiley Online Library
Hepatocellular Carcinoma (HCC) is a malignant tumor with high rate of relapse and
metastasis. Ethanol is a well‐known risk factor for HCC; it promotes the progression and …

Adolescent‐and adult‐initiated alcohol exposure in mice differentially promotes tumorigenesis and metastasis of breast cancer

M Xu, H Li, D Chen, H Wu, W Wen, H Xu… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background Alcohol exposure increases the risk of breast cancer. Alcohol consumption by
adolescents is a serious social and public health issue. This study investigated the impact of …

Lingual lymph node metastases as a prognostic factor in oral squamous cell carcinoma—a retrospective multicenter study

M Kikuchi, H Harada, R Asato, K Hamaguchi, H Tamaki… - Medicina, 2021 - mdpi.com
Backgrounds and Objectives: The epidemiology and prognostic role of lingual lymph node
(LLN) metastasis in patients with oral squamous cell carcinoma (OSCC) remain unclear …