Berberis Vulgaris and Berberine: An Update Review

M Imenshahidi, H Hosseinzadeh - Phytotherapy research, 2016 - Wiley Online Library
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …

Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system

K Zou, Z Li, Y Zhang, H Zhang, B Li, W Zhu… - Acta Pharmacologica …, 2017 - nature.com
It has been widely recognized that inflammation, particularly chronic inflammation, can
increase the risk of cancer and that the simultaneous treatment of inflammation and cancer …

Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Y Liu, B Wang, S Shu, Z Li, C Song, D Liu, Y Niu… - Nature …, 2021 - nature.com
Abstract Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales,
represents an important early-diverging eudicot lineage with diverse medicinal applications …

Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats

X Zhang, Y Zhao, M Zhang, X Pang, J Xu, C Kang, M Li… - 2012 - journals.plos.org
Berberine, a major pharmacological component of the Chinese herb Coptis chinensis, which
was originally used to treat bacterial diarrhea, has recently been demonstrated to be …

Mixed organic acids as antibiotic substitutes improve performance, serum immunity, intestinal morphology and microbiota for weaned piglets

SF Long, YT Xu, L Pan, QQ Wang, CL Wang… - Animal Feed Science …, 2018 - Elsevier
The objective of this experiment was to evaluate the effect of two mixed organic acids (OA)
on performance, serum immunity, intestinal morphology and microbiota of weaned pigs in …

Antioxidant and anti‐inflammatory activities of berberine in the treatment of diabetes mellitus

Z Li, YN Geng, JD Jiang… - … Based Complementary and …, 2014 - Wiley Online Library
Oxidative stress and inflammation are proved to be critical for the pathogenesis of diabetes
mellitus. Berberine (BBR) is a natural compound isolated from plants such as Coptis …

Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe−/− mice

L Zhu, D Zhang, H Zhu, J Zhu, S Weng, L Dong, T Liu… - Atherosclerosis, 2018 - Elsevier
Background and aims Gut microbiota plays a major role in metabolic disorders. Berberine is
used to treat obesity, diabetes and atherosclerosis. The mechanism underlying the role of …

Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases

MD Ferrer, C Busquets-Cortés, X Capó… - Current medicinal …, 2019 - ingentaconnect.com
Inflammation plays a crucial role in the development of many complex diseases and
disorders including autoimmune diseases, metabolic syndrome, neurodegenerative …

Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation

J Luettig, R Rosenthal, C Barmeyer, JD Schulzke - Tissue barriers, 2015 - Taylor & Francis
The epithelial tight junction determines the paracellular water and ion movement in the
intestine and also prevents uptake of larger molecules, including antigens, in an …

Protective effect of berberine against LPS-induced injury in the intestine: a review

F Izadparast, B Riahi-Zajani, F Yarmohammadi… - Cell Cycle, 2022 - Taylor & Francis
Sepsis is a systemic inflammatory condition caused by an unbalanced immunological
response to infection, which affects numerous organs, including the intestines …