Prediction medicine: biomarkers, risk calculators and magnetic resonance imaging as risk stratification tools in prostate cancer diagnosis

DF Osses, MJ Roobol, IG Schoots - International journal of molecular …, 2019 - mdpi.com
This review discusses the most recent evidence for currently available risk stratification tools
in the detection of clinically significant prostate cancer (csPCa), and evaluates diagnostic …

Prostate cancer liquid biopsy biomarkers' clinical utility in diagnosis and prognosis

M Matuszczak, JA Schalken, M Salagierski - Cancers, 2021 - mdpi.com
Simple Summary In prostate cancer, overdiagnosis and overtreatment is a common problem
for clinicians. Accurate diagnosis and prognosis are essential to avoid unnecessary biopsy …

SelectMDx and multiparametric magnetic resonance imaging of the prostate for men undergoing primary prostate biopsy: a prospective assessment in a multi …

M Maggi, F Del Giudice, UG Falagario, A Cocci… - Cancers, 2021 - mdpi.com
Simple Summary Prostate-specific antigen and digital rectal examination, used to guide
prostate biopsy, often result in overdiagnosis of indolent prostate cancer (PCa) while …

[HTML][HTML] Diagnostic accuracy of liquid biomarkers for clinically significant prostate cancer detection: a systematic review and diagnostic meta-analysis of multiple …

T Kawada, SR Shim, F Quhal, P Rajwa… - European Urology …, 2023 - Elsevier
Context Many liquid biomarkers have entered clinical practice with the praise to improve the
detection of clinically significant prostate cancer (csPCa), helping avoid unnecessary …

Changes in prostate-specific antigen testing relative to the revised US Preventive Services Task Force recommendation on prostate cancer screening

MS Leapman, R Wang, H Park, BY James… - JAMA …, 2022 - jamanetwork.com
Importance In April 2017, the US Preventive Services Task Force (USPSTF) published a
draft guideline that reversed its 2012 guidance advising against prostate-specific antigen …

[HTML][HTML] Aptamer-guided extracellular vesicle theranostics in oncology

PHL Tran, D Xiang, TNG Nguyen, TTD Tran, Q Chen… - Theranostics, 2020 - ncbi.nlm.nih.gov
In the past decade, the study of exosomes, nanosized vesicles (50-150 nm) released into
the extracellular space via the fusion of multivesicular bodies with the plasma membrane …

[HTML][HTML] Biomarkers for detection of clinically significant prostate cancer: contemporary clinical data and future directions

NW Eyrich, TM Morgan, JJ Tosoian - Translational Andrology and …, 2021 - ncbi.nlm.nih.gov
Use of serum prostate-specific antigen (PSA) testing for early detection of prostate cancer
appears to reduce cancer-specific mortality. Due to the limited specificity of PSA for clinically …

Lifetime Health and Economic Outcomes of Biparametric Magnetic Resonance Imaging as First-Line Screening for Prostate Cancer: A Decision Model Analysis

R Gulati, B Jiao, R Al-Faouri, V Sharma… - Annals of Internal …, 2024 - acpjournals.org
Background: Contemporary prostate cancer (PCa) screening uses first-line prostate-specific
antigen (PSA) testing, possibly followed by multiparametric magnetic resonance imaging …

Prospective assessment of two-gene urinary test with multiparametric magnetic resonance imaging of the prostate for men undergoing primary prostate biopsy

GM Busetto, F Del Giudice, M Maggi, F De Marco… - World Journal of …, 2021 - Springer
Purpose To evaluate the diagnostic accuracy of SelectMDx and its association with
multiparametric magnetic resonance (mpMRI) in predicting prostate cancer (PCa) and …

Serum and urine biomarkers for detecting clinically significant prostate cancer

MF Becerra, VS Atluri, AS Bhattu, S Punnen - Urologic Oncology: Seminars …, 2021 - Elsevier
Since the “prostate-specific antigen (PSA) era,” we have seen an increase in unnecessary
biopsies, which has ultimately lead to an overtreatment of low-risk cancers. Given the …