Integration of chemokine signaling with non-coding RNAs in tumor microenvironment and heterogeneity in different cancers

S Arora, S Khan, A Zaki, G Tabassum, M Mohsin… - Seminars in Cancer …, 2022 - Elsevier
Chemokines are small secreted proteins that regulate the immune system by signaling
through chemokine receptors to induce immune cell migration, motility, and infiltration into …

Epigenetic regulation of pulmonary inflammation

S Ahmad, XL Zhang, A Ahmad - Seminars in cell & developmental biology, 2024 - Elsevier
Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …

Vitamin-D ameliorates sepsis-induced acute lung injury via augmenting miR-149-5p and downregulating ER stress

S Ahmad, A Zaki, K Manda, A Mohan… - The Journal of Nutritional …, 2022 - Elsevier
Acute lung injury is a life-threatening medical problem induced by sepsis or endotoxins and
may be associated with enhanced Endoplasmic reticulum stress (ER stress). Vitamin-D (Vit …

[HTML][HTML] Acute lung injury caused by sepsis: how does it happen?

B Sun, M Lei, J Zhang, H Kang, H Liu… - Frontiers in Medicine, 2023 - ncbi.nlm.nih.gov
Sepsis is a systemic inflammatory disease caused by severe infections that involves multiple
systemic organs, among which the lung is the most susceptible, leaving patients highly …

The emerging roles of ferroptosis in pathophysiology and treatment of acute lung injury

Y Wang, Z Zhao, Z Xiao - Journal of Inflammation Research, 2023 - Taylor & Francis
Ferroptosis, a programmed cell death discovered in recent years, is an iron-dependent lipid
peroxidation accumulation. Unlike other modes of cell death (autophagy, necroptosis …

Non-coding RNA in idiopathic interstitial pneumonia and Covid-19 pulmonary fibrosis

MS Ali, J Singh, MT Alam, A Chopra, S Arava… - Molecular Biology …, 2022 - Springer
Pulmonary fibrosis is the key feature of majority of idiopathic interstitial pneumonias (IIPs) as
well as many patients with post-COVID-19. The pathogenesis of pulmonary fibrosis is a …

LncRNA THRIL, transcriptionally activated by AP-1 and stabilized by METTL14-mediated m6A modification, accelerates LPS-evoked acute injury in alveolar epithelial …

Q Shi, Z Li, Y Dong, G Yang, M Li - International Immunopharmacology, 2023 - Elsevier
Acute lung injury (ALI) and its extreme manifestation, acute respiratory distress syndrome
(ARDS), are life-threatening diseases in intensive care units. LncRNA THRIL plays a crucial …

Long noncoding RNA: a novel insight into the pathogenesis of acute lung injury

S Dutta, Y Zhu, Y Han, S Almuntashiri, X Wang… - Journal of Clinical …, 2023 - mdpi.com
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
represent an acute stage of lung inflammation where the alveolar epithelium loses its …

Regulation of Pro-Inflammatory Macrophage Polarization via Lipid Nanoparticles Mediated Delivery of Anti-Prostaglandin-E2 siRNA

A Almatroudi, MA Alsahli, MA Syed, AA Khan… - Current Issues in …, 2022 - mdpi.com
Pro-inflammatory macrophage polarization is crucial in acute inflammatory diseases like
Acute lung injury (ALI), and acute respiratory distress syndrome (ARDS). Prostaglandin E2 …

Long noncoding RNA MALAT1 inhibition attenuates sepsis‐induced acute lung injury through modulating the miR‐129‐5p/PAX6/ZEB2 axis

Y Li, W Xiao, X Lin - Microbiology and Immunology, 2023 - Wiley Online Library
This research aimed to investigate the role of the long noncoding RNA metastasis‐
associated lung adenocarcinoma transcript 1 (MALAT1)/microRNA‐129‐5p (miR‐129 …