Des-γ-carboxy prothrombin (DCP) is a prothrombin precursor produced in hepatocellular
carcinoma (HCC). Because of deficiency of vitamin K or γ-glutamyl carboxylase in HCC …

The epithelial–mesenchymal transition (EMT) and acquisition of cancer stem cells (CSCs)‐
like properties are essential steps in the metastasis and postsurgical recurrence of …

The Wnt/β-catenin signaling pathway regulates many aspects of tumor biology, and many
studies have focused on the role of this signaling pathway in tumor cells. However, it is now …

Recent studies have indicated that microRNAs (miRNAs) play an important role in
hepatocellular carcinoma (HCC) progression. In this study, we showed that miR-766-3p was …

Hypoxia plays a key role in tumour initiation and metastasis; one of the mechanisms is to
induce epithelial-mesenchymal transition (EMT). Signal transducer and activator of …

This study examined the role played by hypoxia-inducible factors (HIFs) in malignant
phenotype maintenance and canonical Wnt signaling. Under normoxia, we determined that …

Hepatocellular carcinoma (HCC) is a tumor that exhibits glucometabolic reprogramming,
with a high incidence and poor prognosis. Usually, HCC is not discovered until an advanced …

Pediatric high-grade gliomas (pHGG), including diffuse intrinsic pontine gliomas (DIPG), are
the most lethal types of cancer in children. In recent years, it has become evident that these …

Aberrant Wnt activation has been reported in failing cardiomyocytes. Here we present single
cell transcriptome profiling of hearts with inducible cardiomyocyte-specific Wnt activation (β …

DCLK1 and Lgr5 have recently been identified as markers of quiescent and cycling stem
cells in the small intestinal crypts, respectively. Epithelial–mesenchymal transition (EMT) is a …