▪ Abstract The increasing shortage of human cadaveric organs for purposes of
transplantation has become the critical limiting factor in the number of transplants performed …

The transplantation of pig organs to humans (xenotransplantation) is now receiving serious
consideration because of the shortage of human donors for organ transplants of kidney, liver …

As we enter the new millennium, the prospects for the field of Biomedical Engineering are
bright. Individuals interested in pursuing careers in this field continue to increase and the …

To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

Human anti-pig antibodies were obtained by perfusing pig hearts (n= 4) and kidneys (n= 8)
with human AB or O plasma followed by elution with 3 M NaSCN. The antibodies were …

The shortage of donor organs is a major barrier to clinical organ transplantation. Although
xenotransplantation is considered one of the alternatives to human organ transplantation …

The initiating factor in the hyperacute rejection of pig organs by human or non-human
primates is believed to be related to the presence of preformed" natural" antibodies in the …

The limited availability of deceased human organs and cells for the purposes of clinical
transplantation remains critical worldwide. Despite the increasing utilization of 'high …

The pig-to-primate model is increasingly being utilized as the final preclinical means of
assessing therapeutic strategies aimed at allowing discordant xenotransplantation. We …

An urgent and steadily increasing need exists worldwide for a greater supply of donor
thoracic organs. Xenotransplantation offers the possibility of an unlimited supply of hearts …