Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi
J Pijuan, DF Moreno, G Yahya, M Moisa… - Microbial …, 2023 - Wiley Online Library
Iron is an essential element for all eukaryote organisms because of its redox properties,
which are important for many biological processes such as DNA synthesis, mitochondrial …
which are important for many biological processes such as DNA synthesis, mitochondrial …
The siderophore ferricrocin mediates iron acquisition in Aspergillus fumigatus
I Happacher, M Aguiar, M Alilou, B Abt… - Microbiology …, 2023 - Am Soc Microbiol
The opportunistic fungal pathogen Aspergillus fumigatus utilizes two high-affinity iron uptake
mechanisms, termed reductive iron assimilation (RIA) and siderophore-mediated iron …
mechanisms, termed reductive iron assimilation (RIA) and siderophore-mediated iron …
Regulation of high-affinity iron acquisition, including acquisition mediated by the iron permease FtrA, is coordinated by AtrR, SrbA, and SreA in Aspergillus fumigatus
Iron acquisition is crucial for virulence of the human pathogen Aspergillus fumigatus.
Previous studies indicated that this mold regulates iron uptake via both siderophores and …
Previous studies indicated that this mold regulates iron uptake via both siderophores and …
[HTML][HTML] Fungal siderophore metabolism with a focus on Aspergillus fumigatus: Impact on biotic interactions and potential translational applications
I Happacher, M Aguiar, A Yap, C Decristoforo… - Essays in …, 2023 - ncbi.nlm.nih.gov
Iron is an essential trace element that is limiting in most habitats including hosts for fungal
pathogens. Siderophores are iron-chelators synthesized by most fungal species for high …
pathogens. Siderophores are iron-chelators synthesized by most fungal species for high …
Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its ΔtcsC and Δskn7 mutants reveal a crucial role for Skn7 in the cell wall …
S Schruefer, A Pschibul, SSW Wong, T Sae-Ong… - BMC genomics, 2023 - Springer
Background Aspergillus fumigatus is a major fungal pathogen that causes severe problems
due to its increasing resistance to many therapeutic agents. Fludioxonil is a compound that …
due to its increasing resistance to many therapeutic agents. Fludioxonil is a compound that …
Fonsecaea pedrosoi produces ferricrocin and can utilize different host iron sources
The survival of living organisms depends on iron, one of the most abundant metals in the
Earth's crust. Nevertheless, this micronutrient is poorly available in our aerobic atmosphere …
Earth's crust. Nevertheless, this micronutrient is poorly available in our aerobic atmosphere …
Iron Starvation Induces Ferricrocin Production and the Reductive Iron Acquisition System in the Chromoblastomycosis Agent Cladophialophora carrionii
Iron is a micronutrient required by almost all living organisms. Despite being essential, the
availability of this metal is low in aerobic environments. Additionally, mammalian hosts …
availability of this metal is low in aerobic environments. Additionally, mammalian hosts …
Biomimetic Analogues of the Desferrioxamine E Siderophore for PET Imaging of Invasive Aspergillosis: Targeting Properties and Species Specificity
A Mular, I Hubmann, M Petrik, K Bendova… - Journal of Medicinal …, 2024 - ACS Publications
The pathogenic fungus Aspergillus fumigatus utilizes a cyclic ferrioxamine E (FOXE)
siderophore to acquire iron from the host. Biomimetic FOXE analogues were labeled with …
siderophore to acquire iron from the host. Biomimetic FOXE analogues were labeled with …
The Transcription Factors AcuK and AcuM Influence Siderophore Biosynthesis of Aspergillus fumigatus
P Caballero, A Yap, MJ Bromley, H Haas - Journal of Fungi, 2024 - mdpi.com
The mold Aspergillus fumigatus employs two high-affinity uptake systems, reductive iron
assimilation (RIA) and siderophore-mediated iron acquisition (SIA), for the acquisition of the …
assimilation (RIA) and siderophore-mediated iron acquisition (SIA), for the acquisition of the …
Characterization of Aspergillus fumigatus secretome during sublethal infection of Galleria mellonella larvae
A Curtis, P Dobes, J Marciniak… - Journal of Medical …, 2024 - microbiologyresearch.org
Introduction. The fungal pathogen Aspergillus fumigatus can induce prolonged colonization
of the lungs of susceptible patients, resulting in conditions such as allergic …
of the lungs of susceptible patients, resulting in conditions such as allergic …