Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest
mortality and disability rate of cardiovascular disease. Current studies have shown that …

Background Individuals affected with autism often suffer additional co-morbidities such as
intellectual disability. The genes contributing to autism cluster on a relatively limited number …

Acute ischemic stroke has become the major cause of mortality and disability worldwide.
Following ischemic stroke, the reperfusion injury is mainly mediated by the burst of reactive …

Abstract Ethnopharmacological relevance Dengzhan Xixin injection (DX), a preparation of
extracts from traditional Chinese medicine Erigeron breviscapus (Vaniot) Hand.-Mazz., has …

Background Cerebral ischemia/reperfusion (I/R) is a pathological process that occurs in
ischemic stroke. Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) …

Background As a common cerebrovascular disease (CVD) of the elderly, ischemic stroke
(IS) is characterized by high disability and mortality. Excessive autophagy induced by IS is …

Background ADNP is essential for embryonic development. As such, de novo ADNP
mutations lead to an intractable autism/intellectual disability syndrome requiring …

In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

Background Hypoxic–ischemic encephalopathy (HIE) is a severe anoxic brain injury that
leads to premature mortality or long-term disabilities in infants. Neuroinflammation is a vital …

This study aimed to examine whether Biliverdin, which is a common metabolite of haem, can
alleviate cerebral ischemia reperfusion injury (CIRI) by inhibiting pyroptosis. Here, CIRI was …