Background: Although targeted therapies usually trigger great initial responses in patients,
the efficacy is transient due to tumor metastasis. The formation of pre-metastatic niche was …

Breast cancer (BC) is the second leading cause of cancer-associated deaths among
women. Current strategies aimed at eradicating the primary tumor by targeting the bulk …

Lung cancer is the leading cause of cancer-related death worldwide. Despite intensive
research conducted during the past years, little improvement in overall survival has been …

In post-menopausal breast cancer, obesity is related to invasive tumours that are resistant to
chemotherapy and have a poor outcome. Recent research has revealed that adipocytes co …

Erlotinib, a small-molecule tyrosine kinase inhibitor targeted against the EGF receptor, has
demonstrated survival benefit as a single agent in advanced non-small-cell lung cancer and …

Cancer metastasis is a multistep process that involves tumor cell migration and invasion
through tumor stroma, intravasation into and extravasation out of the blood vessels, and …

Abstract Matrix metalloproteinase-9 (MMP-9), and urokinase plasminogen activator (uPA)
overexpression or/and increased activity are considered causative elements for cancer …

Background: Although radical operation to treat lung cancer is thought to be an important
treatment measure, prognosis of advanced lung cancer is still poor. A reasonable treatment …

WO2017205611A1 - Estrogen receptor modulator combinations - Google Patents
WO2017205611A1 - Estrogen receptor modulator combinations - Google Patents Estrogen …

Background: Lung cancer screening is a challenge. Sputum cytology, chest X-ray, low dose
computed tomography and other screening methods have not proved to be very effective …