Abscisic acid: A conserved hormone in plants and humans and a promising aid to combat prediabetes and the metabolic syndrome

M Magnone, L Sturla, L Guida, S Spinelli, G Begani… - Nutrients, 2020 - mdpi.com
Abscisic acid (ABA) is a hormone with a very long evolutionary history, dating back to the
earliest living organisms, of which modern (ABA-producing) cyanobacteria are likely the …

Recent advances in anxiety disorders: Focus on animal models and pathological mechanisms

H Zhao, M Zhou, Y Liu, J Jiang… - Animal Models and …, 2023 - Wiley Online Library
Anxiety disorders have become one of the most severe psychiatric disorders, and the
incidence is increasing every year. They impose an extraordinary personal and …

Chronic d-ribose and d-mannose overload induce depressive/anxiety-like behavior and spatial memory impairment in mice

K Xu, M Wang, W Zhou, J Pu, H Wang, P Xie - Translational Psychiatry, 2021 - nature.com
The effects of different forms of monosaccharides on the brain remain unclear, though
neuropsychiatric disorders undergo changes in glucose metabolism. This study assessed …

The hyperexcitability of laterodorsal tegmentum cholinergic neurons accompanies adverse behavioral and cognitive outcomes of prenatal stress

M Shabani, M Ilaghi, R Naderi, M Razavinasab - Scientific Reports, 2023 - nature.com
Exposure to prenatal stress (PS) leads to the offspring's vulnerability towards the
development of cognitive and behavioral disorders. Laterodorsal tegmentum (LDT) is a part …

The ABA/LANCL Hormone/Receptor System in the Control of Glycemia, of Cardiomyocyte Energy Metabolism, and in Neuroprotection: A New Ally in the Treatment of …

S Spinelli, M Magnone, L Guida, L Sturla… - International Journal of …, 2023 - mdpi.com
Abscisic acid (ABA), long known as a plant stress hormone, is present and functionally
active in organisms other than those pertaining to the land plant kingdom, including …

The ameliorative effects and mechanisms of abscisic acid on learning and memory

P Liao, QY Wu, S Li, KB Hu, HL Liu, HY Wang… - …, 2023 - Elsevier
Abscisic acid (ABA), a conserved hormone existing in plants and animals, not only regulates
blood glucose and inflammation but also has good therapeutic effects on obesity, diabetes …

Involvement of the serotoninergic system in the anxiolytic action mechanism of a liposomal formulation containing nimodipine (NMD-Lipo)

HKMMC Viana, GL da Silva Oliveira… - Pharmacology …, 2023 - Elsevier
In the search for anxiolytic drugs with fewer adverse effects, calcium blockers were proposed
as a benzodiazepines (BZDs) alternative. In this context, the anxiolytic effect of nimodipine …

[HTML][HTML] Abscisic acid interplays with PPARγ receptors and ameliorates diabetes-induced cognitive deficits in rats

R Kooshki, A Anaeigoudari, M Abbasnejad… - Avicenna Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: This study intended to evaluate if central administration of abscisic acid (ABA)
alone or in combination with GW9662, a peroxisome proliferator–activated receptor γ (PPAR …

Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice

M Shabani, H Ranjbar, M Soti, R Naderi - Brain and Behavior, 2022 - Wiley Online Library
Stressful life increases the risk of mental and psychological disorders and cognitive deficits.
Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians …

Abscisic acid ameliorates motor disabilities in 6-OHDA-induced mice model of Parkinson's disease

M Shabani, M Soti, H Ranjbar, R Naderi - Heliyon, 2023 - cell.com
Parkinson's disease (PD) is characterized by a myriad of symptoms, encompassing both
motor disabilities and cognitive impairments. Recent research has shown that abscisic acid …