Spermatozoa contain highly specialized structural features reflecting unique functions
required for fertilization. Among them, the flagellum is a sperm-specific organelle required to …

Every day, we breathe in more than 10,000 L of air that contains a variety of air pollutants
that can pose negative consequences to lung health. The respiratory mucosa formed by the …

Bronchiectasis is a complex, heterogeneous disorder defined by both a radiological
abnormality of permanent bronchial dilatation and a clinical syndrome. There are multiple …

Exome sequencing has been commonly used to characterize rare diseases by selecting
multiplex families or singletons with an extreme phenotype (EP) and searching for rare …

Male infertility due to spermatogenesis defects affects millions of men worldwide. However,
the genetic etiology of the vast majority remains unclear. Here we describe three men with …

Background Nasal transcriptomics can provide an accessible window into asthma
pathobiology. Objective Our goal was to move beyond gene signatures of asthma to identify …

In this review, we have selected several outstanding studies from the American Journal of
Respiratory and Critical Care Medicine (AJRCCM), the American Journal of Respiratory Cell …

Background: Hearing loss remains an important global health problem that is potentially
addressed through early identification of a genetic etiology, which helps to predict outcomes …

Introduction Asthenoteratozoospermia is one of the most common causes of male infertility.
Several genes have been identified as genetic causative factors, but there is a considerable …

Background This research characterized mucociliary clearance (MCC) in young children
with cystic fibrosis (CF). Methods Fourteen children (5–7 years old) with CF underwent: two …