Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

Prostate and breast cancer are the second most and most commonly diagnosed cancer in
men and women worldwide, respectively. The American Cancer Society estimates that …

Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …

Ginsenoside Rg5 has been implicated in a variety of diseases. However, it is unknown
whether Ginsenoside Rg5 can protect against hypoxia‐induced neonatal rat cardiomyocytes …

Theranostics are a multifunctional approach using nanoparticles for combined diagnostic
and therapeutic purposes. The hybrid nanoparticles that are applied for these purposes are …

Cisplatin is used to treat a variety of tumors, but dose-limiting toxicities or intrinsic and
acquired resistance limit its application in many types of cancer including breast. Cisplatin …

Background Nanoparticles have an enormous potential for development in biomedical
applications, such as gene or drug delivery. In our study, we examined the efficacy of p53 …

Generally, definite intestine targeting and immediate drug releasing are both important for
the treatment of colon cancer via oral administration of anti-cancer drugs. We developed a …

Silica nanoparticles as a nonviral vector for in vivo gene therapy neither surface
functionalized SiNp1 is neither “a cationic ion” nor a surface (encapsulation) nor SiNp2 …

Abstract Development of efficient biodegradable, environmentally responsive, biocompatible
and non-toxic delivery system is needed for efficient gene delivery. As well known …