Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

Current paradigms of cancer-centric therapeutics are usually not sufficient to eradicate the
malignancy, as the cancer stroma may prompt tumour relapse and therapeutic resistance …

The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …

It is now well established that cancer cells co-exist within a complex environment with
stromal cells and depend for their growth and dissemination on tight and plastic interactions …

Tumorigenesis is not only determined by the intrinsic properties of cancer cells but also by
their interactions with components of the tumor microenvironment (TME). Tumor‐associated …

Extracellular matrix (ECM) plays a central and dynamic role in the creation of tumor
microenvironment. Herein we discuss the emerging biophysical and biochemical aspects of …

WNT2 acts as a pro-angiogenic factor in placental vascularization and increases
angiogenesis in liver sinusoidal endothelial cells (ECs) and other ECs. Increased WNT2 …

Platelets play significant and varied roles in cancer progression, as detailed throughout this
review series, via direct interactions with cancer cells and by long-range indirect interactions …

Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a
hallmark of solid tumors. This process is driven by an imbalance between pro-and anti …