Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are three
endogenously produced gases with important functions in the vasculature, immune defense …

Solid tumors are complex entities that actively shape their microenvironment to create a
supportive environment for their own growth. Angiogenesis and immune suppression are …

New piperazine–chalcone hybrids and related pyrazoline derivatives have been designed
and synthesised as potential vascular endothelial growth factor receptor-2 (VEGFR-2) …

In this paper we review the mechanisms of the antitumor effects of Hypericum perforatum
L.(St. John's wort, SJW) and its main active component hyperforin (HPF). SJW extract is …

Objective: The purpose of this study is to explore the effects of microRNA-29b (miR-29b)
regulating MAPK/ERK and PI3K/Akt signaling pathways on angiogenesis in endometrial …

One of the hallmarks of cancer is angiogenesis, a series of events leading to the formation of
the abnormal vascular network required for tumor growth, development, progression, and …

Cancers are complex diseases having several unique features, commonly described as
'hallmarks of cancer'. Among them, altered signaling pathways are the common …

Abstract Background Enterococcus faecalis (Efa) has been shown to be a “driver bacteria” in
the occurrence and development of colorectal cancer (CRC). This study aims to explore the …

Simple Summary The inflammatory adipose microenvironment in obesity plays a crucial role
in cancer development and metastases. By focusing on adipocytes and macrophages, as …

High dietary intake of fruits and vegetables is consistently associated with a reduced risk of
common human cancers. The specific mechanisms of action of most phytochemicals in …