Relapse and rehospitalisation rates in patients with schizophrenia: effects of second generation antipsychotics

JG Csernansky, EK Schuchart - CNS drugs, 2002 - Springer
Recent studies suggest that the risk of relapse in patients with schizophrenia is
approximately 3.5% per month. Predictors of more frequent relapses include poor …

Partial compliance and patient consequences in schizophrenia: our patients can do better

SJ Keith, JM Kane - Journal of Clinical Psychiatry, 2003 - psychiatrist.com
Objective: The primary objective of this review is to evaluate the strategies used to improve
patient compliance with antipsychotic medication in the treatment of schizophrenia. Data …

Paliperidone extended-release tablets for prevention of symptom recurrence in patients with schizophrenia: a randomized, double-blind, placebo-controlled study

M Kramer, G Simpson, V Maciulis… - Journal of clinical …, 2007 - journals.lww.com
We evaluated the efficacy of paliperidone extended-release (ER), an investigational
psychotropic agent, in delaying symptom recurrence in adult patients with schizophrenia …

Effect of antipsychotic medication alone vs combined with psychosocial intervention on outcomes of early-stage schizophrenia: a randomized, 1-year study

X Guo, J Zhai, Z Liu, M Fang, B Wang… - Archives of general …, 2010 - jamanetwork.com
Context Antipsychotic drugs are limited in their ability to improve the overall outcome of
schizophrenia. Adding psychosocial treatment may produce greater improvement in …

Lack of insight in schizophrenia: impact on treatment adherence

PF Buckley, DA Wirshing, P Bhushan, JM Pierre… - CNS drugs, 2007 - Springer
People with schizophrenia commonly lack insight, that is, they are unaware of their illness
and the consequences thereof. One of the most important consequences of lack of insight is …

Patients on atypical antipsychotic drugs: another high-risk group for type 2 diabetes

MEJ Lean, FG Pajonk - Diabetes care, 2003 - Am Diabetes Assoc
Patients with schizophrenia are more likely than the general population to develop diabetes,
which contributes to a high risk of cardiovascular complications; individuals with …

The critical treatment window of clozapine in treatment-resistant schizophrenia: secondary analysis of an observational study

B Yoshimura, Y Yada, R So, M Takaki, N Yamada - Psychiatry research, 2017 - Elsevier
Previous studies have suggested that a delay in initiating clozapine is one of the predictors
of outcomes in treatment-resistant schizophrenia (TRS). However, whether there is a critical …

Atypical antipsychotics and glucose dysregulation: a systematic review

H Jin, JM Meyer, DV Jeste - Schizophrenia research, 2004 - Elsevier
Atypical antipsychotics (AAP) have been widely used for the management of patients with
schizophrenia and other psychotic disorders since they were introduced during the past …

Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial

EYH Chen, CLM Hui, MML Lam, CPY Chiu, CW Law… - Bmj, 2010 - bmj.com
Objective To study rates of relapse in remitted patients with first episode psychosis who
either continued or discontinued antipsychotic drugs after at least one year of maintenance …

Medication nonadherence and treatment outcome in patients with schizophrenia or schizoaffective disorder with suboptimal prior response.

JP Lindenmayer, H Liu-Seifert… - Journal of Clinical …, 2009 - psychiatrist.com
Objective: To examine the impact of medication nonadherence on treatment outcome in
schizophrenia and potential risk factors for nonadherence. Method: A post hoc analysis of a …