[HTML][HTML] Treatment of glaucoma with natural products and their mechanism of action: An update

RH Sim, SR Sirasanagandla, S Das, SL Teoh - Nutrients, 2022 - mdpi.com
Glaucoma is one of the leading causes of irreversible blindness. It is generally caused by
increased intraocular pressure, which results in damage of the optic nerve and retinal …

[HTML][HTML] Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii

I Pateraki, J Andersen-Ranberg, NB Jensen… - Elife, 2017 - elifesciences.org
Forskolin is a unique structurally complex labdane-type diterpenoid used in the treatment of
glaucoma and heart failure based on its activity as a cyclic AMP booster. Commercial …

Progress in heterologous biosynthesis of forskolin

H Ju, C Zhang, W Lu - Journal of Industrial Microbiology and …, 2021 - academic.oup.com
Forskolin, a class of labdane-type diterpenoid, has significant medicinal value in anticancer,
antiasthmatic, antihypertensive, and heart-strengthening treatments. The main source of …

Identification of potential cultivation areas for centelloside-specific elite chemotypes of Centella asiatica (L.) using ecological niche modeling

SP Singh, A Misra, B Kumar, D Adhikari… - Industrial Crops and …, 2022 - Elsevier
Centella asiatica (L.) is used in the treatment of neuropsychiatric disorders, gastro-intestinal
problems, and wound healing in the Ayurveda system of medicine. The species is well …

Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

H Ju, C Zhang, S He, W Nan, W Lu - Applied Microbiology and …, 2022 - Springer
Forskolin, one of the primary active metabolites of labdane-type diterpenoids, exhibits
significant medicinal value, such as anticancer, antiasthmatic, and antihypertensive …

Simultaneous HPTLC-UV quantification of colchicine and gloriosine alkaloids in the natural population of Gloriosa superba L., collected from Eastern Ghats of India …

A Misra, B Kumar, P Shukla… - Journal of Liquid …, 2020 - Taylor & Francis
Intra-specific chemical variability in the natural population of Gloriosa superba from Eastern
Ghats (India) was recorded through validated HPTLC method and in vitro antiarthritic activity …

Chemotaxonomic studies on natural population of Gloriosa superba (L.) collected from Gangetic plain (India) and their invitro antigout activity for the identification of …

A Misra, S Srivastava, S Kumar, PK Shukla… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Gloriosa superba L.(Colchicaceae) is used in the
treatment of gout and rheumatism as a traditional medicine dates back to 1810. It has also …

Chemodiversity and molecular variability in the natural populations (India) of Gloriosa superba (L.) and correlation with eco-geographical factors for the identification …

A Misra, P Mishra, B Kumar, PK Shukla, M Kumar… - Fitoterapia, 2021 - Elsevier
Gloriosa superba L. has economic significance due to colchicine, a bioactive compound
used for gout. In present study metabolic and molecular variability in natural population of …

Biotechnological interventions for the production of forskolin, an active compound from the medicinal plant, Coleus forskohlii

PT Roshni, PD Rekha - Physiology and Molecular Biology of Plants, 2024 - Springer
Coleus forskohlii, an Indian-origin medicinal plant is the sole natural source of the labdane
terpenoid forskolin (C22H34O7), with growing demand. Forskolin emerged as an industrially …

[HTML][HTML] Forskolin improves male reproductive complications caused by hyperglycemia in type 2 diabetic rats

M Naghibi, HT Nasrabadi, JS Rad… - … Journal of Fertility & …, 2023 - ncbi.nlm.nih.gov
Background: In many diabetic patients, spermatogenesis complications are frequent causing
infertility problems. This study aimed to demonstrate the effect of Forskolin on male …