[HTML][HTML] Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

[HTML][HTML] The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

[HTML][HTML] Candidemia among Iranian patients with severe COVID-19 admitted to ICUs

A Arastehfar, T Shaban, H Zarrinfar, M Roudbary… - Journal of Fungi, 2021 - mdpi.com
As a novel risk factor, COVID-19 has led to an increase in the incidence of candidemia and
an elevated mortality rate. Despite being of clinical importance, there is a lack of data …

[HTML][HTML] Enhancing the antifungal activity of griseofulvin by incorporation a green biopolymer-based nanocomposite

A Shehabeldine, H El-Hamshary, M Hasanin… - Polymers, 2021 - mdpi.com
Fungal biofilms have caused several medical problems, resulting in significant morbidity and
mortality as well as poor response to antifungal drugs. The current study was designed to …

[HTML][HTML] Clonal Candidemia Outbreak by Candida parapsilosis Carrying Y132F in Turkey: Evolution of a Persisting Challenge

A Arastehfar, S Hilmioğlu-Polat, F Daneshnia… - Frontiers in cellular …, 2021 - frontiersin.org
As the second leading etiological agent of candidemia in Turkey and the cause of severe
fluconazole-non-susceptible (FNS) clonal outbreaks, Candida parapsilosis emerged as a …

[HTML][HTML] Raman Spectroscopy of Oral Candida Species: Molecular-Scale Analyses, Chemometrics, and Barcode Identification

G Pezzotti, M Kobara, T Nakaya, H Imamura… - International journal of …, 2022 - mdpi.com
Oral candidiasis, a common opportunistic infection of the oral cavity, is mainly caused by the
following four Candida species (in decreasing incidence rate): Candida albicans, Candida …

[HTML][HTML] Invasive fungal diseases in Africa: a critical literature review

F Bongomin, BE Ekeng, W Kibone, L Nsenga, R Olum… - Journal of Fungi, 2022 - mdpi.com
Invasive fungal diseases (IFDs) are of huge concern in resource-limited settings, particularly
in Africa, due to the unavailability of diagnostic armamentarium for IFDs, thus making …

Genetically related micafungin-resistant Candida parapsilosis blood isolates harbouring novel mutation R658G in hotspot 1 of Fks1p: a new challenge?

A Arastehfar, F Daneshnia… - Journal of …, 2021 - academic.oup.com
Background Echinocandin resistance rarely occurs in clinical Candida parapsilosis isolates
and the underlying mechanism is unknown. Objectives To determine the prevalence of …

[HTML][HTML] The emerging threat antifungal-resistant Candida tropicalis in humans, animals, and environment

R Lima, FC Ribeiro, AL Colombo… - Frontiers in Fungal …, 2022 - frontiersin.org
Antifungal resistance in humans, animals, and the environment is an emerging problem.
Among the different fungal species that can develop resistance, Candida tropicalis is …