[HTML][HTML] Diabetes mellitus and diabetic foot ulcer: Etiology, biochemical and molecular based treatment strategies via gene and nanotherapy

AVA Mariadoss, AS Sivakumar, CH Lee… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a collection of metabolic and pathophysiological disorders
manifested with high glucose levels in the blood due to the inability of β-pancreatic cells to …

[Retracted] Multifunctional Therapeutic Approach of Nanomedicines against Inflammation in Cancer and Aging

MM Rahman, F Islam, S Afsana Mim… - Journal of …, 2022 - Wiley Online Library
Cancer is a fatal disorder that affects people across the globe, yet existing therapeutics are
ineffective. The development of submicrometer transport for optimizing the biodistribution of …

[HTML][HTML] Disentangling mitochondria in Alzheimer's disease

A Johri - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

[HTML][HTML] In vitro studies on nasal formulations of nanostructured lipid carriers (NLC) and solid lipid nanoparticles (SLN)

CP Costa, S Barreiro, JN Moreira, R Silva, H Almeida… - Pharmaceuticals, 2021 - mdpi.com
The nasal route has been used for many years for the local treatment of nasal diseases.
More recently, this route has been gaining momentum, due to the possibility of targeting the …

[HTML][HTML] Nanomedicine: A Promising way to manage Alzheimer's disease

NH Khan, M Mir, EE Ngowi, U Zafar… - … in Bioengineering and …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a devastating disease of the aging population characterized by
the progressive and slow brain decay due to the formation of extracellular plaques in the …

Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders

ME Neganova, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …

[HTML][HTML] Advancements in the blood–brain barrier penetrating nanoplatforms for brain related disease diagnostics and therapeutic applications

S Thangudu, FY Cheng, CH Su - Polymers, 2020 - mdpi.com
Noninvasive treatments to treat the brain-related disorders have been paying more
significant attention and it is an emerging topic. However, overcoming the blood brain barrier …

[HTML][HTML] Intranasal drug administration in Alzheimer-type dementia: Towards clinical applications

R Taléns-Visconti, JV de Julián-Ortiz, O Vila-Busó… - Pharmaceutics, 2023 - mdpi.com
Alzheimer-type dementia (ATD) treatments face limitations in crossing the blood–brain
barrier and systemic adverse effects. Intranasal administration offers a direct route to the …

[PDF][PDF] Lipid nanostructures for targeting brain cancer

H Nsairat, D Khater, F Odeh, F Al-Adaileh, S Al-Taher… - Heliyon, 2021 - cell.com
Advancements in both material science and bionanotechnology are transforming the health
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …

Targeting the central nervous system: From synthetic nanoparticles to extracellular vesicles—Focus on Alzheimer's and Parkinson's disease

S Hernando, E Santos‐Vizcaíno… - Wiley …, 2023 - Wiley Online Library
Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are an accelerating global health problem as life expectancy rises worldwide …