The presence of insoluble aggregates of amyloid β (Aβ) in the form of neuritic plaques (NPs)
is one of the main features that define Alzheimer's disease. Studies have suggested that the …

Neurodegenerative disorders are heterogeneous, debilitating, and incurable groups of brain
disorders that have common features including progressive degeneration of the structure …

Age is the strongest risk factor for Alzheimer's disease (AD). In recent years, the relationship
between aging and AD has been widely studied, with anti-aging therapeutics as the …

Neurodegenerative disorders (NDs) affect a great number of people worldwide and also
have a significant socio-economic impact on the aging population. In this context …

Abstract Neoplasm (Glioblastoma) and Alzheimer's disease (AD) comprise two of the most
chronic psychological ailments. Glioblastoma is one of the aggressive and prevalent …

Highlights•Alzheimer's disease (AD) is drastically lacking of curative treatment.•The interest
of nanocarriers for the approved drugs in AD treatment has been shown.•Drug repurposing …

The important causes of microglial dysfunction include continuous accumulation of amyloid
beta (Aβ) fibrils, elevated reactive oxygen species (ROS), and hypoxia. They may be the key …

Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that
constitutes the third most common cause of death among elderly individuals. AD patients …

Alzheimer's disease (AD) is one of the leading causes of death worldwide, with no definitive
diagnosis or known cure. The aggregation of Tau protein into neurofibrillary tangles (NFTs) …

Nano-based systems provide many advantages, including eluding gastrointestinal and first-
pass metabolism of the drug and improving the potential advantage of reduced doses of …