[HTML][HTML] N-Acetyl-Aspartyl-Glutamate in Brain Health and Disease

C Morland, K Nordengen - International Journal of Molecular Sciences, 2022 - mdpi.com
N-acetyl-aspartyl-glutamate (NAAG) is the most abundant dipeptide in the brain, where it
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …

[HTML][HTML] Astrocyte-neuron communication mediated by the Notch signaling pathway: focusing on glutamate transport and synaptic plasticity

KX Li, M Lu, MX Cui, XM Wang… - Neural Regeneration …, 2023 - journals.lww.com
Maintaining glutamate homeostasis after hypoxic ischemia is important for synaptic function
and neural cell activity, and regulation of glutamate transport between astrocyte and neuron …

The dynamic transcriptomic response of the goldfish brain under chronic hypoxia

S Cortes, E Farhat, GGM Talarico… - … and Physiology Part D …, 2024 - Elsevier
Oxygen is essential to fuel aerobic metabolism. Some species evolved mechanisms to
tolerate periods of severe hypoxia and even anoxia in their environment. Among them …

The Notch pathway regulates autophagy after hypoxic–ischemic injury and affects synaptic plasticity

K Li, M Lu, M Cui, X Wang, Y Zheng - Brain Structure and Function, 2023 - Springer
Following neonatal hypoxic–ischemia (HI) injury, it is crucial factor to reconstruct neural
circuit and maintain neural network homeostasis for neurological recovery. A dynamic …

[HTML][HTML] The potential relationship between HIF-1α and amino acid metabolism after hypoxic ischemia and dual effects on neurons

K Li, Y Zheng, X Wang - Frontiers in Neuroscience, 2021 - frontiersin.org
Hypoxia inducible factor (HIF) is one of the major transcription factors through which cells
and tissues adapt to hypoxic-ischemic injury. However, the specific mechanism by which HIF …

[HTML][HTML] The regulatory role of NAAG-mGluR3 signaling on cortical synaptic plasticity after hypoxic ischemia

K Li, M Lu, M Cui, X Wang, Y Zheng - Cell Communication and Signaling, 2022 - Springer
Background Synapses can adapt to changes in the intracerebral microenvironment by
regulation of presynaptic neurotransmitter release and postsynaptic neurotransmitter …

由Notch 信号通路介导的星形胶质细胞-神经元通讯: 关注谷氨酸转运和突触可塑性

KX Li, M Lu, MX Cui, XM Wang, Y Zheng - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
维持神经递质的平衡是星形胶质细胞对神经元的支持作用之一. 其中, 谷氨酸的平衡是维持突触
功能和神经细胞活动的一个重要方面. 然而, 研究谷氨酸的动态变化, 谷氨酸转运的分子机制以及 …